The impact of genetic interactions on DNA methylation in breast cancer

Sproul, Duncan (Principal Investigator)

Deanery of Molecular, Genetic and Population Health Sciences

Status	Active
Effective start/end date	1/09/16 → 31/08/22

Funding

UK-based charities: £1,381,258.00

3 Article

Genotype effects contribute to variation in longitudinal methylome patterns in older people
Zhang, Q., Marioni, R., Robinson, M. R., Higham, J., Sproul, D., Wray, N. R., Deary, I., Mcrae, A. F. & Visscher, P. M., 22 Oct 2018, In: Genome Medicine. 10, 75, p. 1-11
Research output: Contribution to journal › Article › peer-review

Open Access
File
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Cole, J. J., Robertson, N. A., Rather, M. I., Thomson, J. P., McBryan, T., Sproul, D., Wang, T., Brock, C., Clark, W., Ideker, T., Meehan, R. R., Miller, R. A., Brown-Borg, H. M. & Adams, P. D., 28 Mar 2017, In: Genome Biology. 18, 58.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment
El-Sharkawi, D., Sproul, D., Allen, C. G., Feber, A., Wright, M., Hills, R. K., Linch, D. C. & Gale, R. E., 12 Oct 2017, In: Haematologica.
Research output: Contribution to journal › Article › peer-review

Open Access
File