Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
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2025
Rapid autofluorescence flow cytometric analysis of agonist-induced neutrophil and eosinophil polarization reveals novel insights into 5-oxo-ETE-mediated granulocyte activation
Fernando, A. J., Rossi, F., Docherty, D., Popravko, A., Masters, L., Houston, B., Gupta, R., Dhaliwal, K. & Rossi, A. G., 6 Nov 2025, In: Journal of inflammation. 22, 47.Research output: Contribution to journal › Article › peer-review
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Temporal Dichotomy of Neutrophil Function in Acute Liver Injury and Repair
Cartwright, J., Potey, P., Livingstone, E., Campana, L., Starkey Lewis, P. J., Oremek, M., Gachanja, N., Rinaldi, G., Aird, R., Man, T. Y., Fernando, A., Simpson, J., Homer, N. Z. M., Barth, N., Addison, M., Ashmore-Harris, C., Candela, M., Kilpatrick, A., Vermeren, M. & Robb, C. & 4 others, , Jul 2025, In: JHEP Reports. 7, 7, p. 1-18 18 p., 101417.Research output: Contribution to journal › Article › peer-review
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2023
Fish Erythrocyte Extracellular Traps (FEETs) are an evolutionary conserved cellular process triggered by different stimuli
Rinaldi, G., Álvarez De Haro, N., Fernando, A. J., Desbois, A. P., Robb, C. & Rossi, A. G., 24 Feb 2023, (E-pub ahead of print) In: Fish and Shellfish Immunology.Research output: Contribution to journal › Article › peer-review
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2022
SILAC-based quantitative proteomics to investigate the eicosanoid associated inflammatory response in activated macrophages
Brace, N., Megson, I. L., Rossi, A. G., Doherty, M. K. & Whitfield, P. D., 1 Sept 2022, In: Journal of inflammation. 19, 1, 19 p., 12.Research output: Contribution to journal › Article › peer-review
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Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration
Bruton, F., Kaveh, A., Ross Stewart, K., Matrone, G., Oremek, M., Solomonidis, E., Tucker, C., Mullins, J., Lucas, C. D., Brittan, M., Taylor, J. M., Rossi, A. G. & Denvir, M. A., 9 Jun 2022, In: Developmental Cell. 57, 12, p. 1512-1528Research output: Contribution to journal › Article › peer-review
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Inhibition of cyclin-dependent kinase 9 downregulates cytokine production without detrimentally affecting human monocyte-derived macrophage viability
McHugh, B., Stephen, J., Robb, C., Fox, S., Kipari, T., Cartwright, J., Haslett, C., Duffin, R., Lucas, C. D. & Rossi, A. G., 26 May 2022, In: Frontiers in Cell and Developmental Biology. 10, 905315.Research output: Contribution to journal › Article › peer-review
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2021
Dysregulation of Prostaglandins, Leukotrienes and Lipoxin A4 in Bronchiectasis
Bedi, P., Zeigler, K., Whitfield, P. D., Davidson, D. J., Rossi, A. G. & Hill, A., 17 Nov 2021, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Article › peer-review
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Selective CDK9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish
Kaveh, A., Bruton, F., Oremek, M., Tucker, C. S., Taylor, J. M., Mullins, J. J., Rossi, A. G. & Denvir, M. A., 15 Sept 2021, In: Development.Research output: Contribution to journal › Article › peer-review
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The Outcome of Neutrophil-T Cell Contact Differs Depending on Activation Status of Both Cell Types
Minns, D., Smith, K. J., Hardisty, G., Rossi, A. G. & Gwyer Findlay, E., 30 Mar 2021, In: Frontiers in Immunology. 12Research output: Contribution to journal › Article › peer-review
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2020
A fluorogenic peptide-based smartprobe for the detection of neutrophil extracellular traps and inflammation
Rios, M. R., Garoffolo, G., Rinaldi, G., Megia-fernandez, A., Ferrari, S., Robb, C. T., Rossi, A. G., Pesce, M. & Bradley, M., 8 Dec 2020, In: Chemical Communications. 57, 1, p. 97-100Research output: Contribution to journal › Article › peer-review
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Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury
MacFarlane, J. G., Dorward, D. A., Ruchaud-Sparagano, M.-H., Scott, J., Lucas, C. D., Rossi, A. G. & Simpson, A. J., 30 Oct 2020, In: Journal of inflammation.Research output: Contribution to journal › Article › peer-review
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Non-steroidal anti-inflammatory drugs, prostaglandins and COVID-19
Robb, C., Goepp, M., Rossi, A. G. & Yao, C., 23 Jul 2020, In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
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Eosinophil deficiency promotes aberrant repair and adverse remodelling following acute myocardial infarction
Toor, I., Rückerl, D., Mair, I., Ainsworth, R., Meloni, M., Spiroski, A.-M., Benezech, C., Felton, J. M., Thomson, A. W., Caporali, A., Keeble, T., Tang, K. H., Rossi, A., Newby, D., Allen, J. E. & Gray, G., 8 Jul 2020, (E-pub ahead of print) In: JACC: Basic to Translational Science.Research output: Contribution to journal › Article › peer-review
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Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation
Felton, J. M., Dorward, D. A., Cartwright, J., Potey, P. M. D., Robb, C. T., Gui, J., Craig, R. W., Schwarze, J., Haslett, C., Duffin, R., Dransfield, I., Lucas, C. D. & Rossi, A. G., 1 Jul 2020, In: Thorax. 75, 7, p. 600-605Research output: Contribution to journal › Article › peer-review
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Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing
Ho, G.-T., Cartwright, J. A., Thompson, E. J., Bain, C. C. & Rossi, A. G., 31 Mar 2020, In: Inflammatory Bowel Diseases.Research output: Contribution to journal › Article › peer-review
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2019
Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart
Taylor, J. M., Nelson, C. J., Bruton, F. A., Kaveh, A., Buckley, C., Tucker, C. S., Rossi, A. G., Mullins, J. J. & Denvir, M. A., 15 Nov 2019, In: Nature Communications. 10, 5173.Research output: Contribution to journal › Article › peer-review
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A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites
McCormick, B., Craig, H. E., Chu, J. Y., Carlin, L. M., Canel, M., Wollweber, F., Toivakka, M., Michael, M., Astier, A. L., Norton, L., Lilja, J., Felton, J. M., Sasaki, T., Ivaska, J., Hers, I., Dransfield, I., Rossi, A. G. & Vermeren, S., 15 Sept 2019, In: The Journal of Immunology. 203, 6, p. 1579-1588Research output: Contribution to journal › Article › peer-review
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Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice
Toor, I. S., Rückerl, D., Mair, I., Thomson, A., Rossi, A. G., Newby, D. E., Allen, J. E. & Gray, G. A., 23 May 2019, (E-pub ahead of print) In: Clinical & Experimental Immunology.Research output: Contribution to journal › Article › peer-review
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Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa
McHugh, B. J., Wang, R., Li, H.-N., Beaumont, P. E., Kells, R., Stevens, H., Young, L., Rossi, A. G., Gray, R. D., Dorin, J. R., Gwyer Findlay, E. L., Brough, D. & Davidson, D. J., 12 Apr 2019, In: PLoS Pathogens. 15, 4, e1007694.Research output: Contribution to journal › Article › peer-review
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Inflammation Resolution and the Induction of Granulocyte Apoptosis by Cyclin-Dependent Kinase Inhibitor Drugs
Cartwright, J. A., Lucas, C. D. & Rossi, A. G., 19 Feb 2019, In: Frontiers in pharmacology. 10Research output: Contribution to journal › Article › peer-review
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2018
Immune complex-induced neutrophil functions: A focus on cell death
Vermeren, S., Karmakar, U. & Rossi, A. G., 7 Nov 2018, In: European journal of clinical investigation. p. e12948Research output: Contribution to journal › Review article › peer-review
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Blood Neutrophils are Reprogrammed in Bronchiectasis
Bedi, P., Davidson, D. J., McHugh, B. J., Rossi, A. G. & Hill, A. T., 1 Oct 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 7, p. 880-890Research output: Contribution to journal › Article › peer-review
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Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis
Barth, N. D., Marwick, J. A., Heeb, M. J., Gale, A. J., Rossi, A. G. & Dransfield, I., 24 Sept 2018, In: The Journal of Immunology.Research output: Contribution to journal › Article › peer-review
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Cerebral concussion primes the lungs for subsequent neutrophil-mediated injury
Humphries, D., O'Neill, S., Scholefield, E., Dorward, D. A., MacKinnon, A., Rossi, A. G., Haslett, C., Andrews, P., Rhodes, J. & Dhaliwal, K., 27 Jun 2018, (E-pub ahead of print) In: Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
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Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation
Marwick, J. A., Mills, R., Kay, O., Michail, K., Stephen, J., Rossi, A. G., Dransfield, I. & Hirani, N., 4 Jun 2018, (E-pub ahead of print) In: Cell Death and Disease. 9, 6Research output: Contribution to journal › Article › peer-review
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Purine metabolism controls innate lymphoid cell function and protects against intestinal injury
Crittenden, S., Cheyne, A., Adams, A., Forster, T., Robb, C. T., Felton, J., Ho, G.-T., Ruckerl, D., Rossi, A. G., Anderton, S. M., Ghazal, P., Satsangi, J., Howie, S. E. & Yao, C., 14 May 2018, (E-pub ahead of print) In: Immunology & Cell Biology.Research output: Contribution to journal › Article › peer-review
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Facilitation of IL-22 production from innate lymphoid cells by prostaglandin E2 prevents experimental lung neutrophilic inflammation
Felton, J. M., Duffin, R., Robb, C. T., Crittenden, S., Anderton, S. M., Howie, S. E. M., Whyte, M. K. B., Rossi, A. G. & Yao, C., 24 Mar 2018, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Letter › peer-review
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Mer-mediated eosinophil efferocytosis regulates resolution of allergic airway inflammation
Felton, J., Lucas, C. D., Dorward, D. A., Duffin, R., Kipari, T., Vermeren, S., Robb, C., Macleod, K., Serrels, B., Schwarze, J., Haslett, C., Dransfield, I. & Rossi, A. G., 8 Feb 2018, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › peer-review
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2017
The “Phagocytic Synapse” and Clearance of Apoptotic Cells
Barth, N. D., Marwick, J. A., Vendrell, M., Rossi, A. G. & Dransfield, I., 4 Dec 2017, In: Frontiers in Immunology. 8Research output: Contribution to journal › Article › peer-review
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Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in Acute Respiratory Distress Syndrome
Dorward, D. A., Lucas, C. D., Doherty, M. K., Chapman, G. B., Scholefield, E., Conway-Morris, A., Felton, J. M., Kipari, T., Humphries, D. C., Robb, C. T., Simpson, A. J., Whitfield, P. D., Haslett, C., Dhaliwal, K. & Rossi, A. G., Oct 2017, In: Thorax. 72, 10, p. 928-936 9 p.Research output: Contribution to journal › Article › peer-review
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Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis
Robb, C. T., McSorley, H. J., Lee, J., Aoki, T., Yu, C., Crittenden, S., Astier, A., Felton, J. M., Parkinson, N., Ayele, A., Breyer, R. M., Anderton, S. M., Narumiya, S., Rossi, A. G., Howie, S., Guttman-Yassky, E., Weller, R. B. & Yao, C., 3 Jun 2017, In: Journal of Allergy and Clinical Immunology. 141, 1, p. 152-162Research output: Contribution to journal › Article › peer-review
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The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome
Dorward, D. A., Felton, J. M., Robb, C. T., Craven, T., Kipari, T., Walsh, T. S., Haslett, C., Kefala, K., Rossi, A. G. & Lucas, C. D., Feb 2017, In: Thorax. 72, 2, p. 182-185 4 p.Research output: Contribution to journal › Article › peer-review
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2016
Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo
Hoodless, L. J., Lucas, C. D., Duffin, R., Denvir, M. A., Haslett, C., Tucker, C. S. & Rossi, A. G., 11 Nov 2016, (E-pub ahead of print) In: Scientific Reports. 36980 .Research output: Contribution to journal › Article › peer-review
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11β-Hydroxysteroid Dehydrogenase type 1 is expressed in neutrophils and restrains an inflammatory response in male mice
Coutinho, A. E., Kipari, T. M. J., Zhang, Z., Esteves, C. L., Lucas, C. D., Gilmour, J. S., Webster, S. P., Walker, B. R., Hughes, J., Savill, J. S., Seckl, J. R., Rossi, A. G. & Chapman, K. E., 4 May 2016, (E-pub ahead of print) In: Endocrinology. 157, 7, p. 2928-2936 9 p.Research output: Contribution to journal › Article › peer-review
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2015
Crosstalk between monocytes and myometrial smooth muscle in culture generates synergistic pro-inflammatory cytokine production and enhances myocyte contraction, with effects opposed by progesterone
Rajagopal, S. P., Hutchinson, J. L., Dorward, D., Rossi, A. G. & Norman, J. E., 22 May 2015, In: Molecular Human Reproduction.Research output: Contribution to journal › Article › peer-review
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The Role of Formylated Peptides and Formyl Peptide Receptor 1 in Governing Neutrophil Function during Acute Inflammation
Dorward, D., Lucas, C. D., Chapman, G., Haslett, C., Dhaliwal, K. & Rossi, A. G., 16 Mar 2015, In: The American Journal of Pathology. 185, 5, p. 1172–1184Research output: Contribution to journal › Literature review › peer-review
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Wogonin Induces Eosinophil Apoptosis and Attenuates Allergic Airway Inflammation
Lucas, C. D., Dorward, D. A., Sharma, S., Rennie, J., Felton, J. M., Alessandri, A. L., Duffin, R., Schwarze, J., Haslett, C. & Rossi, A. G., 15 Mar 2015, In: American Journal of Respiratory and Critical Care Medicine. 191, 6, p. 626-636 11 p.Research output: Contribution to journal › Article › peer-review
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2014
Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial
RELIEVE Trial Investigators, Jiwaji, Z., Nunn, K. P., Conway-Morris, A., Simpson, A. J., Wyncoll, D., Rossi, A. G., Walsh, T. S. & Oatey, K. (Member of Group Organisation), 10 Oct 2014, In: Transfusion. 54, 10, p. 2404-2411 8 p.Research output: Contribution to journal › Article › peer-review
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Invertebrate extracellular phagocyte traps show that chromatin is an ancient defence weapon
Robb, C. T., Dyrynda, E. A., Gray, R. D., Rossi, A. G. & Smith, V. J., 13 Aug 2014, In: Nature Communications. 5, 11 p., 4627.Research output: Contribution to journal › Article › peer-review
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Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung
Lucas, C. D., Dorward, D. A., Tait, M. A., Fox, S., Marwick, J. A., Allen, K. C., Robb, C. T., Hirani, N., Haslett, C., Duffin, R. & Rossi, A. G., Jul 2014, In: Mucosal Immunology. 7, 4, p. 857-868 12 p.Research output: Contribution to journal › Article › peer-review
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Atorvastatin as a stable treatment in bronchiectasis: a randomised controlled trial
Mandal, P., Chalmers, J. D., Graham, C., Harley, C., Sidhu, M. K., Doherty, C., Govan, J. W., Sethi, T., Davidson, D. J., Rossi, A. G. & Hill, A. T., 1 Jun 2014, In: The Lancet Respiratory Medicine. 2, 6, p. 455-463 9 p.Research output: Contribution to journal › Article › peer-review
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Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation
Brittan, M., Barr, L. C., Anderson, N., Conway-Morris, A., Duffin, R., Marwick, J. A., Rossi, F., Johnson, S., Dhaliwal, K., Hirani, N., Rossi, A. G. & Simpson, A. J., 31 Mar 2014, In: Journal of inflammation. 11, 1, 9.Research output: Contribution to journal › Article › peer-review
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Apoptotic cell clearance: basic biology and therapeutic potential
Poon, I. K. H., Lucas, C. D., Rossi, A. G. & Ravichandran, K. S., Mar 2014, In: Nature Reviews Immunology. 14, 3, p. 166-180 15 p.Research output: Contribution to journal › Literature review › peer-review
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Swimming Against the Tide: Drugs Drive Neutrophil Reverse Migration
Lucas, C. D., Hoodless, L. J. & Rossi, A. G., 26 Feb 2014, In: Science Translational Medicine. 6, 225, 3 p., ARTN 225fs9.Research output: Contribution to journal › Article
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2013
Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments
Marwick, J. A., Dorward, D. A., Lucas, C. D., Jones, K. O., Sheldrake, T. A., Fox, S., Ward, C., Murray, J., Brittan, M., Hirani, N., Duffin, R., Dransfield, I., Haslett, C. & Rossi, A. G., 20 Aug 2013, In: Journal of Leukocyte Biology. 94, 6, p. 1285-1292Research output: Contribution to journal › Article › peer-review
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A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation
Barr, L. C., Brittan, M., Conway Morris, A., McAuley, D. F., McCormack, C., Fletcher, A. M., Richardson, H., Connell, M., Patel, D., Wallace, W., Rossi, A. G., Davidson, D. J., Manson, L., Turner, M., Hirani, N., Walsh, T. S., Anderson, N. H., Dhaliwal, K. & Simpson, A. J., Aug 2013, In: American Journal of Respiratory and Critical Care Medicine. 188, 4, p. 449-455Research output: Contribution to journal › Article › peer-review
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Emerging importance of omega-3 fatty acids in the innate immune response: Molecular mechanisms and lipidomic strategies for their analysis
Maskrey, B. H., Megson, I. L., Rossi, A. G. & Whitfield, P. D., Aug 2013, In: Molecular Nutrition & Food Research. 57, 8, p. 1390-1400 11 p.Research output: Contribution to journal › Literature review › peer-review
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Resolution of inflammation: Mechanisms and opportunity for drug development
Alessandri, A. L., Sousa, L. P., Lucas, C. D., Rossi, A. G., Pinho, V. & Teixeira, M. M., Aug 2013, In: Pharmacology and Therapeutics. 139, 2, p. 189-212 24 p.Research output: Contribution to journal › Literature review › peer-review
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Technical advance: autofluorescence-based sorting: rapid and nonperturbing isolation of ultrapure neutrophils to determine cytokine production
Dorward, D. A., Lucas, C. D., Alessandri, A. L., Marwick, J. A., Rossi, F., Dransfield, I., Haslett, C., Dhaliwal, K. & Rossi, A. G., Jul 2013, In: Journal of Leukocyte Biology. 94, 1, p. 193-202 10 p.Research output: Contribution to journal › Article › peer-review
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Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents
Montanaro, G., Bertinaria, M., Rolando, B., Fruttero, R., Lucas, C., Dorward, D. A., Rossi, A. G., Megson, I. L. & Gasco, A., 1 Apr 2013, In: Bioorganic and Medicinal Chemistry. 21, 7, p. 2107-2116 10 p.Research output: Contribution to journal › Article › peer-review
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