The role of intelectins in the Th-2 mediated expulsion of gastrointestinal nematodes

Project Details

Layman's description

This project studies the gentic basis for differences in worm infection severity. It utilises different strains of mice that differ in susceptible to worn infection of the gut. We identified a specific genetic locus that underlies this differnece and characterised its organisation withi the genome.

Key findings

Amplification of gene sequences within the intelectin locus underlies differing susceptibility of mice to gastrointestinal nematode infection.
Effective start/end date1/05/0830/11/10


  • BBSRC: £330,163.00


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