The roles of a universally conserved DNA-and RNA-binding domain in controlling MRSA virulence and antibiotic resistance

Project Details

StatusActive
Effective start/end date1/04/24 → 31/03/29

Funding

  • Medical Research Council: £876,456.81

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
View full fingerprint

  • SCORCH2: A Generalized Heterogeneous Consensus Model for High-Enrichment Interaction-Based Virtual Screening

    Chen, L., Blay, V., Ballester, P. J. & Houston, D. R., 20 Aug 2025, (E-pub ahead of print) In: Advanced Science. 51 p., e08318.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

    Herasymenko, O., Silva, M., Abu-Saleh, A.A.-A., Ahmad, A., Alvarado-Huayhuaz, J. A., Arce, O. E. A., Armstrong, R. J., Arrowsmith, C., Bachta, K. E., Beck, H., Berta, D., Bieniek, M. K., Blay, V., Bolotokova, A., Bourne, P. E., Breznik, M., Brown, P. J., Campbell, A. D. G., Carosati, E. & Chau, I. & 83 others, Cole, D. J., Cree, B., Dehaen, W., Denzinger, K., dos Santos Machado, K., Dunn, I., Durai, P., Edfeldt, K., Edwards, A., Fayne, D., Friston, K., Ghiabi, P., Gibson, E., Guenther, J., Gunnarsson, A., Hillisch, A., Houston, D. R., Halborg Jensen, J., Harding, R. J., Harris, K. S., Hoffer, L., Hogner, A., Horton, J. T., Houliston, S., Hultquist, J. F., Hutchinson, A., Irwin, J. J., Jukič, M., Kandwal, S., Karlova, A., Katis, V. L., Kich, R. P., Kireev, D., Koes, D., Inniss, N. L., Lessel, U., Liu, S., Loppnau, P., Lu, W., Martino, S., McGibbon, M., Meiler, J., Mettu, A., Money-Kyrle, S., Moretti, R., Moroz, Y. S., Muvva, C., Newman, J. A., Obendorf, L., Paige, B., Pandit, A., Park, K., Perveen, S., Pirie, R., Poda, G., Protopopov, M., Pütter, V., Ricci, F., Roper, N. J., Rosta, E., Rzhetskaya, M., Sabnis, Y., Satchell, K. J. F., Schmitt Kremer, F., Scott, T., Seitova, A., Steinmann, C., Talagayev, V., Tarkhanova, O. O., Tatum, N. J., Treleaven, D., Velasque Werhli, A., Walters, W. P., Wang, X., Wells, J., Wells, G., Westermaier, Y., Wolber, G., Wortmann, L., Zhang, J., Zhao, Z., Zheng, S. & Schapira, M., 14 Jul 2025, In: Journal of Chemical Information and Modeling. 65, 13, p. 6884-6898 31 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerisation on binding dsRNA.

    Winterbourne, S., Jayachandran, U., Zou, J., Rappsilber, J., Granneman, S. & Cook, A. G., 11 Apr 2025, In: Nucleic Acids Research. 53, 6, 15 p., gkaf204.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File