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Therapeutic Targeting of Pathogenic Scar-associated Macrophages in the Fibrotic Niche of Chronic Liver Disease
Ramachandran, Prakash
(Principal Investigator)
Deanery of Clinical Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Active
Effective start/end date
1/03/22
→
28/02/27
Funding
Medical Research Council:
£2,379,335.01
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Ontogeny
Medicine and Dentistry
100%
Tissue Injury
Medicine and Dentistry
100%
Myeloid Cell
Medicine and Dentistry
100%
Apoplexy
Medicine and Dentistry
100%
Bile Acid
Medicine and Dentistry
100%
Basement Membrane
Medicine and Dentistry
100%
Hepatic Stellate Cell
Medicine and Dentistry
100%
Cerebrovascular Accident
Neuroscience
100%
Research output
Research output per year
2024
2024
2024
2
Article
Research output per year
Research output per year
Aberrant basement membrane production by hepatic stellate cells in MASLD is attenuated by the bile acid analog INT-767
Ramachandran, P.
,
Brice, M.
,
Sutherland, E.
,
Hoy, A.
,
Papachristoforou, E.
,
Li, J.
,
Turner, F.
,
Kendall, T. J.
,
MARWICK, JOHN.
,
Carragher, N. O.
,
Oro, D.
,
Feigh, M.
,
Leeming, D. J.
,
Nielsen, M. J.
,
Karsdal, M. A.
,
Hartmann, N.
,
Erickson, M.
,
Adorini, L.
,
Roth, J. D.
&
Fallowfield, J. A.
,
1 Dec 2024
,
In:
Hepatology Communications.
8
,
12
, e0574.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Basement Membrane
100%
Bile Acid
100%
Hepatic Stellate Cell
100%
Steatohepatitis
87%
Farnesoid X Receptor
62%
Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity
Patir, A.
,
Barrington, J.
,
Szymkowiak, S.
,
Brezzo, G.
,
Straus, D.
,
Alfieri, A.
,
Lefevre, L.
,
Liu, Z.
,
Ginhoux, F.
,
Henderson, N. C.
,
Horsburgh, K.
,
Ramachandran, P.
&
McColl, B. W.
,
28 May 2024
,
In:
Cell Reports.
43
,
5
, 114250.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Apoplexy
100%
Myeloid Cell
100%
Tissue Injury
100%
Ontogeny
100%
Myeloid
100%