To delineate immune mechanisms for limiting asthma development and severity

Status	Finished
Effective start/end date	1/02/18 → 31/01/23

Metabolic regulation by prostaglandin E2 impairs lung group 2 innate lymphoid cell responses
Robb, C. T., Zhou, Y., Felton, J. M., Zhang, B., Goepp, M., Jheeta, P., Smyth, D. J., Duffin, R., Vermeren, S., Breyer, R. M., Narumiya, S., McSorley, H. J., Maizels, R. M., Schwarze, J. K. J., Rossi, A. G. & Yao, C., 1 Oct 2022, (E-pub ahead of print) In: Allergy.
Research output: Contribution to journal › Article › peer-review

Open Access
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Prostaglandin E2 directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF- signalling
Goepp, M., Crittenden, S., Zhou, Y., Rossi, A. G., Narumiya, S. & Yao, C., 16 Sep 2021, In: Immunology.
Research output: Contribution to journal › Article › peer-review

Open Access
Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
Crittenden, S., Goepp, M., Pollock, J., Robb, C., Smyth, D. J., Zhou, Y., Andrews, R., Tyrrell, V., Gkikas, K., Adima, A., O'Connor, R. A., Davies, L., Li, X-F., Yao, H. X., Ho, G-T., Zheng, X., Mair, A., Vermeren, S., Qian, B-Z., Mole, D. J., & 12 othersGerasimidis, K., Schwarze, J., Breyer, R. M., Arends, M. J., O'donnell, V. B., Iredale, J. P., Anderton, S. M., Narumiya, S., Maizels, R. M., Rossi, A. G., Howie, S. E. M. & Yao, C., 12 Feb 2021, In: Science Advances.
Research output: Contribution to journal › Article › peer-review

Open Access
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Project Details