Towards a mechanistic understanding of RNA processing machines

Cook, Atlanta (Principal Investigator)

School of Biological Sciences

Status	Finished
Effective start/end date	1/10/16 → 1/10/22

Funding

UK-based charities: £1,639,486.00

A nowhere-to-hide mechanism ensures complete piRNA-directed DNA methylation
Chowdhury, T., Boyle, S., Zoch, A., Xiang, X., Dias Mirandela, M., Fieler, H., Spanos, C., Zou, J., Kelly, D., Bickmore, W. A., Cook, A. G. & O'Carroll, D., 19 Feb 2026, In: Nature. 650, 8102, p. 779-785 26 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line
Zoch, A., Konieczny, G., Auchynnikava, T., Stallmeyer, B., Rotte, N., Heep, M., Berrens, R. V., Schito, M., Kabayama, Y., Schöpp, T., Kliesch, S., Houston, B., Nagirnaja, L., O’Bryan, M. K., Aston, K. I., Conrad, D. F., Rappsilber, J., Allshire, R. C., Cook, A. G. & Tüttelmann, F. & 1 others, O’Carroll, D., 21 Mar 2024, In: Molecular Cell. 84, 6, p. 1021 27 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Structure of SALL4 zinc-finger domain reveals link between AT-rich DNA binding and Okihiro syndrome
Watson, J., Pantier, R., Jayachandran, U., Chhatbar, K., Alexander-Howden, B., Kruusvee, V., Prendecki, M., Bird, A. P. & Cook, A. G., Mar 2023, In: Life Science Alliance. 6, 3, 13 p., e202201588.
Research output: Contribution to journal › Article › peer-review

Open Access
File

The use of missense variations in functional annotation of the human ARID family of DNA binding proteins
Cook, A. (Creator) & Deák, G. (Creator), Edinburgh DataShare, 26 Nov 2021
DOI: 10.7488/ds/3190, https://doi.org/10.1101/2021.11.17.468850
Dataset