Transcriptional control of macrophage function in the pig and its relationship to infectious disease susceptibility

Research output

Research output per year 2010 2012 2013 2019

• 14 Article
• 5 Meeting abstract
• 2 Abstract

Research output per year

Research output per year

Search results

• 2019

  The effect of race training on the basal gene expression of alveolar macrophages derived from Standardbred racehorses

  Karagianni, A., Summers, K., Couroucé, A., Depecker, M., McGorum, B., Hume, D. & Pirie, R., 29 Jan 2019, (E-pub ahead of print) In: Journal of equine veterinary science.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Alveolar Macrophage 100%
  • Gene Expression 100%
  • Standardbred Horse 100%
  • Racehorses 100%
  • Standardbred 100%
• 2015

  Identification and annotation of conserved promoters and macrophage-expressed genes in the pig genome

  Robert, C., Kapetanovic, R., Beraldi, D., Watson, M., Archibald, A. L. & Hume, D. A., 20 Nov 2015, In: BMC Genomics. 16, 1, p. 970

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Promoter Region 100%
  • Regulatory Element 75%
  • Gene Expression 75%
  • Orthology 75%
• 2014

  Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115)

  Moffat, L., Rothwell, L., Garcia-Morales, C., Sauter, K. A., Kapetanovic, R., Gow, D. & Hume, D. A., 11 Jul 2014, In: Developmental and Comparative Immunology. 47, 1, p. 123-128 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Monoclonal Antibody 100%
  • Interleukin 34 50%
  • Macrophage 50%
  • Mononuclear Phagocyte System 25%
  • Alveolar Macrophage 25%

• Design and development of exome capture sequencing for the domestic pig (Sus scrofa)

  Robert, C., Fuentes Utrilla, P., Troup, K., Loecherbach, J., Turner, F., Talbot, R., Archibald, A. L., Mileham, A., Deeb, N., Hume, D. A. & Watson, M., 3 Jul 2014, In: BMC Genomics. 15, 1, p. 550

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exome 100%
  • Domestic Pig 100%
  • Single Nucleotide Polymorphism 25%
  • Indel 25%
  • Expressed Sequence Tag 25%
• 2013

  The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide

  Kapetanovic, R., Fairbairn, L., Downing, A., Beraldi, D., Sester, D. P., Freeman, T. C., Tuggle, C. K., Archibald, A. L. & Hume, D. A., 28 Aug 2013, In: BMC Genomics. 14, 1, 581.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Breed 100%
  • Alveolar Macrophage 75%
  • Infectious Disease 25%
  • Transcriptome 25%

• Comparative Analysis of Monocyte Subsets in the Pig

  Fairbairn, L., Kapetanovic, R., Beraldi, D., Sester, D. P., Tuggle, C. K., Archibald, A. L. & Hume, D. A., Jun 2013, In: The Journal of Immunology. 190, 12, p. 6389-6396

  Research output: Contribution to journal › Article › peer-review

  • CD14 100%
  • CD163 66%
  • Growth Factor 16%
  • Scavenger Receptor 16%
  • Gene Expression 16%

• Structural and functional annotation of the porcine immunome

  Dawson, H. D., Loveland, J. E., Pascal, G., Gilbert, J. G. R., Uenishi, H., Mann, K. M., Sang, Y., Zhang, J., Carvalho-Silva, D., Hunt, T., Hardy, M., Hu, Z., Zhao, S.-H., Anselmo, A., Shinkai, H., Chen, C., Badaoui, B., Berman, D., Amid, C. & Kay, M. & 30 others, Lloyd, D., Snow, C., Morozumi, T., Cheng, R.P.-Y., Bystrom, M., Kapetanovic, R., Schwartz, J. C., Kataria, R., Astley, M., Fritz, E., Steward, C., Thomas, M., Wilming, L., Toki, D., Archibald, A. L., Bed'Hom, B., Beraldi, D., Huang, T.-H., Ait-Ali, T., Blecha, F., Botti, S., Freeman, T. C., Giuffra, E., Hume, D. A., Lunney, J. K., Murtaugh, M. P., Reecy, J. M., Harrow, J. L., Rogel-Gaillard, C. & Tuggle, C. K., 15 May 2013, In: BMC Genomics. 14, 16 p., ARTN 332.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Immune Response 100%
  • Immune Response Gene 80%
  • Infectious Agent 60%
  • Cladistics 40%
  • Gene Duplication 40%

• Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34).

  Gow, D. J., Garceau, V., Pridans, C., Gow, A., Simpson, K. E., Gunn-Moore, D. & Hume, D., 2013, In: Cytokine. 61, 2, p. 630-638 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Colony Stimulating Factor 100%
  • Cerebrospinal Fluid 100%
  • Species Difference 100%
  • Macrophage Colony-Stimulating Factor 100%
  • Interleukin 34 100%

• The equine alveolar macrophage: functional and phenotypic comparisons with peritoneal macrophages

  Karagianni, A., Kapetanovic, R., McGorum, B., Hume, D. & Pirie, R., 2013, In: Veterinary Immunology and Immunopathology. 155, 4, p. 219-228

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage 100%
  • Alveolar Macrophage 100%
  • Neoplasm 30%
  • Indoleamine 2,3-dioxygenase 25%
  • Equine Respiratory Disease 10%
• 2012

  A gene expression atlas of the domestic pig

  Freeman, T. C., Ivens, A., Baillie, J. K., Beraldi, D., Barnett, M. W., Dorward, D., Downing, A., Fairbairn, L., Kapetanovic, R., Raza, S., Tomoiu, A., Alberio, R., Wu, C., Su, A. I., Summers, K. M., Tuggle, C. K., Archibald, A. L. & Hume, D. A., 15 Nov 2012, In: BMC Biology. 10, n/a, 21 p., 90.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Digestive Function 100%

• Analyses of pig genomes provide insight into porcine demography and evolution

  Groenen, M. A. M., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H.-J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C. & Auvil, L. & 116 others, Badaoui, B., Beattie, C. W., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Zhan Bujie, [. V., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S.-H., Chow, W., Clark, R. C., Clee, C., Crooijmans, R. P. M. A., Dawson, H. D., Dehais, P., De Sapio, F., Dibbits, B., Drou, N., Du, Z.-Q., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G., Fowler, K. E., Fredholm, M., Fritz, E., Gilbert, J. G. R., Giuffra, E., Gorodkin, J., Griffin, D. K., Harrow, J. L., Hayward, A., Howe, K., Hu, Z.-L., Humphray, S. J., Hunt, T., Hornshoj, H., Jeon, J.-T., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J.-H., Kim, K.-W., Kim, T.-H., Larson, G., Lee, K., Lee, K.-T., Leggett, R., Lewin, H. A., Li, Y., Liu, W., Loveland, J. E., Lu, Y., Lunney, J. K., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M. P., Narayan, J., Dinh Truong Nguyen, [. V., Ni, P., Oh, S.-J., Onteru, S., Panitz, F., Park, E.-W., Park, H.-S., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J. M., Rodriguez-Zas, S., Rohrer, G. A., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J. G., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B. R., Sperber, G., Stadler, P., Sweedler, J. V., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerle, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. & Schook, L. B., 15 Nov 2012, In: Nature. 491, 7424, p. 393-398 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Duroc Pig 100%

• Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide

  Kapetanovic, R., Fairbairn, L., Beraldi, D., Sester, D. P., Archibald, A. L., Tuggle, C. K. & Hume, D. A., 2012, In: The Journal of Immunology. 188, 7, p. 3382-94 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage Inflammatory Protein 3alpha 100%

• Prediction of Altered 3'- UTR miRNA-Binding Sites from RNA-Seq Data: The Swine Leukocyte Antigen Complex (SLA) as a Model Region

  Endale Ahanda, M.-L., Fritz, E. R., Estellé, J., Hu, Z.-L., Madsen, O., Groenen, M. A. M., Beraldi, D., Kapetanovic, R., Hume, D. A., Rowland, R. R. R., Lunney, J. K., Rogel-Gaillard, C., Reecy, J. M. & Giuffra, E., 2012, In: PLoS ONE. 7, 11, 11 p., e48607.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • MicroRNA 100%
  • RNA Sequencing 100%
  • Binding Site 100%
  • Leukocyte 100%
  • 3' Untranslated Region 100%
• 2011

  The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease

  Fairbairn, L., Kapetanovic, R., Sester, D. P. & Hume, D. A., Jun 2011, In: Journal of Leukocyte Biology. 89, 6, p. 855-871 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Innate Immune System 100%
  • Mononuclear Phagocyte System 100%
  • Macrophage Differentiation 33%
  • Experimental Model 33%
  • Preclinical Study 33%