Transfer from Sheffield: Regulation or neutrophilic inflammation by the HIF/PHD pathway

Walmsley, Sarah (Principal Investigator)

Deanery of Clinical Sciences

Status	Finished
Effective start/end date	1/09/14 → 31/12/17

Funding

UK-based charities: £1,252,945.00

11 Article

NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD
Ryan, E., Sadiku, P., Coelho, P., Watts, E. R., Zhang, A., Howden, A. J. M., Sanchez Garcia, M. A., Bewley, M. A., Cole, J., McHugh, B., Vermaelen, W., Ghesquiere, B., Carmeliet, P., Rodriguez Blanco, G., von Kriegsheim, A., Sanchez, Y., Rumsey, W., Callahan, J. F., Cooper, G., Parkinson, N., & 8 othersBaillie, J. K., Cantrell, D., McCafferty, J., Choudhury, G., Singh, D., Dockrell, D. H., Whyte, M. K. B. & Walmsley, S. R., 1 Feb 2023, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation
Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R., Reyes, L., Cooper, G., Clark, S., Lewis, D., Kelly, V., & 22 othersSpanos, C., Musgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N., Rostron, A. J., Baillie, J. K., Clohisey, S., Pridans, C., Campana, L., Starkey Lewis, P., Simpson, A. J., Dockrell, D. H., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. B. & Walmsley, S. R., 27 May 2022, In: Nature Immunology.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
Watts, E. R., Howden, A. J. M., Morrison, T., Sadiku, P., Hukelmann, J. L., Von Kriegsheim, A., Ghesquière, B., Murphy, F., Mirchandani, A. S., Humphries, D. C., Grecian, R., Ryan, E. M., Coelho, P., Rodriguez-blanco, G., Plant, T. M., Dickinson, R. S., Finch, A. J., Vermaelen, W., Cantrell, D. A., Whyte, M. K. B., & 1 othersWalmsley, S. R., 6 Apr 2021, (E-pub ahead of print) In: Journal of Clinical Investigation.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Transfer from Sheffield: Regulation or neutrophilic inflammation by the HIF/PHD pathway

Project Details

Funding

Fingerprint

NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

Transfer from Sheffield: Regulation or neutrophilic inflammation by the HIF/PHD pathway

Project Details

Funding

Fingerprint

Research output

NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD

Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism