Research output per year
Research output per year
Research output
- 11 Article
- 11 results
Search results
-
2023
NRF2 activation reprogrammes defects in oxidative metabolism to restore macrophage function in COPD
Ryan, E., Sadiku, P., Coelho, P., Watts, E. R., Zhang, A., Howden, A. J. M., Sanchez Garcia, M. A., Bewley, M. A., Cole, J., McHugh, B., Vermaelen, W., Ghesquiere, B., Carmeliet, P., Rodriguez Blanco, G., von Kriegsheim, A., Sanchez, Y., Rumsey, W., Callahan, J. F., Cooper, G. & Parkinson, N. & 8 others, , 1 Feb 2023, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2022
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation
Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R., Reyes, L., Cooper, G., Clark, S., Lewis, D. & Kelly, V. & 22 others, , 27 May 2022, In: Nature Immunology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2021
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
Watts, E. R., Howden, A. J. M., Morrison, T., Sadiku, P., Hukelmann, J. L., Von Kriegsheim, A., Ghesquière, B., Murphy, F., Mirchandani, A. S., Humphries, D. C., Grecian, R., Ryan, E. M., Coelho, P., Rodriguez-blanco, G., Plant, T. M., Dickinson, R. S., Finch, A. J., Vermaelen, W., Cantrell, D. A. & Whyte, M. K. B. & 1 others, , 6 Apr 2021, (E-pub ahead of print) In: Journal of Clinical Investigation.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
Sadiku, P., Willson, J. A., Ryan, E. M., Sammut, D., Coelho, P., Watts, E. R., Grecian, R., Young, J. M., Bewley, M., Arienti, S., Mirchandani, A. S., Sanchez Garcia, M. A., Morrison, T., Zhang, A., Reyes, L., Griessler, T., Jheeta, P., Paterson, G. G., Graham, C. J. & Thompson, J. P. & 16 others, , 2 Feb 2021, In: Cell Metabolism. 33, 2, p. 411-423.e4Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2020
Semaphorin 3F signaling actively retains neutrophils at sites of inflammation
Plant, T., Eamsamarng, S., Sanchez-Garcia, M. A., Reyes, L., Renshaw, S. A., Coelho, P., Mirchandani, A. S., Morgan, J.-M., Ellett, F. E., Morrison, T., Humphries, D., Watts, E. R., Murphy, F., Raffo-Iraolagoitia, X. L., Zhang, A., Cash, J. L., Loynes, C., Elks, P. M., Van Eeden, F. & Carlin, L. M. & 3 others, , 1 Jun 2020, In: Journal of Clinical Investigation. 130, 6, p. 3221-3237Research output: Contribution to journal › Article › peer-review
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2019
IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo
Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D. & Jenkins, S. J. & 2 others, , 15 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Hypoxia and reprogramming of host pathogen interactions
Ryan, E. M., Whyte, M. K. & Walmsley, S. R., 27 Nov 2018, (E-pub ahead of print) In: Current opinion in physiology. 7, p. 15-20Research output: Contribution to journal › Article › peer-review
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2017
Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo
Dickinson, R. S., Murphy, F., Doherty, C., Williams, S., Mirchandani, A., Willson, J. A., Scotti, J. S., Preston, G., Schofield, C. J., Whyte, M. K. B. & Walmsley, S. R., 26 Oct 2017, In: Wellcome Open Research . 2, p. 104Research output: Contribution to journal › Article › peer-review
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Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
Sadiku, P., Willson, J. A., Dickinson, R., Murphy, F., Harris, A., Lewis, A., Sammut, D., Mirchandani, A. S., Ryan, E., Watts, E. R., Thompson, A. A. R., Marriott, H. M., Dockrell, D. H., Taylor, C. T., Schneider, M., Maxwell, P. H., Chilvers, E. R., Mazzone, M., Moral, V. & Pugh, C. W. & 6 others, , 1 Sept 2017, In: Journal of Clinical Investigation. 127, 9, p. 3407-3420 14 p.Research output: Contribution to journal › Article › peer-review
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Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
Thompson, A. A. R., Dickinson, R. S., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N. & Preston, J. A. & 15 others, , 24 Feb 2017, In: Science Immunology. 2, 8, eaal2861.Research output: Contribution to journal › Article › peer-review
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2015
Exploring the HIFs, Buts and Maybes of Hypoxia Signalling in Disease: Lessons From Zebrafish Models
Elks, P. M., Renshaw, S. A., Meijer, A. H., Walmsley, S. & Van Eeden, F. J., 1 Nov 2015, In: Disease Models and Mechanisms. 8, 11, p. 1349-1360Research output: Contribution to journal › Article › peer-review
Open AccessFile