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What are the mechanisms by which myelination in theCNS is established and refined?
Ffrench-Constant, Charles
(Principal Investigator)
Deanery of Clinical Sciences
Anne Rowling Regenerative Neurology Clinic
Edinburgh Neuroscience
University of Edinburgh
Overview
Fingerprint
Research output
(3)
Project Details
Status
Finished
Effective start/end date
1/03/15
→
30/11/20
Funding
UK-based charities:
£2,095,194.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Myelin Sheath
Medicine & Life Sciences
100%
Neuroepithelial Cells
Medicine & Life Sciences
93%
Endothelins
Medicine & Life Sciences
74%
Oligodendroglia
Medicine & Life Sciences
71%
Axons
Medicine & Life Sciences
56%
Extracellular Matrix
Medicine & Life Sciences
54%
Cell Culture Techniques
Medicine & Life Sciences
49%
Stem Cells
Medicine & Life Sciences
47%
Research output
Research output per year
2017
2017
2019
2021
2021
3
Article
Research output per year
Research output per year
Intrinsic and adaptive myelination - a sequential mechanism for smart wiring in the brain
Bechler, M. E.
,
Swire, M.
&
Ffrench-Constant, C.
,
22 Aug 2017
, (E-pub ahead of print)
In:
Developmental neurobiology.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Myelin Sheath
100%
Axons
84%
Oligodendroglia
53%
Brain
47%
Synapses
44%
Combinatorial ECM Arrays Identify Cooperative Roles for Matricellular Proteins in Enhancing the Generation of TH+ Neurons From Human Pluripotent Cells
Ahmed, M.
,
Owens, M. J. S.
,
Toledo, E. M.
,
Arenas, E.
,
Bradley, M.
&
Ffrench-constant, C.
,
1 Dec 2021
, (E-pub ahead of print)
In:
Frontiers in Cell and Developmental Biology.
9
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Neuroepithelial Cells
100%
Extracellular Matrix
58%
Cell Culture Techniques
52%
Stem Cells
50%
Neurons
42%
Endothelin signalling mediates experience-dependent myelination in the CNS
Swire, M.
,
Kotelevtsev, Y.
,
Webb, D. J.
,
Lyons, D. A.
&
ffrench-Constant, C.
,
5 Nov 2019
,
In:
eLIFE.
8
,
23 p.
, e49493.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Endothelins
100%
Social Isolation
53%
Oligodendroglia
47%
Myelin Sheath
44%
Protein Kinase C-epsilon
31%