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When there is not enough telomerase: telomerase insufficiency and genome integrity
Makovets, Sveta
(Principal Investigator)
School of Biological Sciences
Overview
Fingerprint
Research output
(2)
Project Details
Status
Finished
Effective start/end date
1/08/18
→
31/07/23
Funding
MRC:
£2,682,759.00
View all
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Mitosis
Biochemistry, Genetics and Molecular Biology
100%
Nucleoprotein
Biochemistry, Genetics and Molecular Biology
100%
Cell Death
Biochemistry, Genetics and Molecular Biology
100%
Telomerase
Biochemistry, Genetics and Molecular Biology
100%
Helicase
Biochemistry, Genetics and Molecular Biology
100%
Regulatory Mechanism
Biochemistry, Genetics and Molecular Biology
50%
Homologous Recombination
Biochemistry, Genetics and Molecular Biology
50%
DNA
Biochemistry, Genetics and Molecular Biology
50%
Research output
Research output per year
2023
2023
2024
2024
2
Article
Research output per year
Research output per year
The functional significance of the RPA- and PCNA-dependent recruitment of Pif1 to DNA
Kotenko, O.
&
Makovets, S.
,
12 Apr 2024
,
In:
EMBO Reports.
25
,
4
,
p. 1734-1751
18 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Helicase
100%
Telomerase
100%
Nucleic Acid
50%
DNA-binding Protein
50%
Molecular Model
50%
The inability to disassemble Rad51 nucleoprotein filaments leads to aberrant mitosis and cell death
Andriuskevicius, T.
,
Dubenko, A.
&
Makovets, S.
,
15 May 2023
,
In:
Biomedicines.
11
,
5
,
25 p.
, 1450.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Mitosis
100%
Cell Death
100%
Nucleoprotein
100%
Homologous Recombination
50%
Cell Survival
50%