Projects per year
assembled genomes (MAGs). These MAGs were used as reference database to investigate the effect of diet restriction on the composition and functional potential of the rumen microbiome of African cattle. Results: We report 1,200 newly discovered MAGs from the rumen of Boran cattle. 850 were de-replicated and their uniqueness confirmed with pairwise comparisons (based on Mash distances) between African MAGs and other publicly available genomes from the rumen. A genome-centric investigation into sub-optimal diets highlighted a statistically significant effecton rumen microbial abundance profiles and a previously 24 unobserved relationship between whole microbiome shifts in functional potential and taxon-level associations in metabolic pathways.
Conclusions: This study is the first to identify 1,200 high quality African rumen-specific MAGs and provides further insight into the rumen function in harsh environments with food scarcity. The genomic information from the rumen microbiome of an indigenous African cattle breed sheds light on the microbiome contribution to rumen functionality and constitutes a vital resource in addressing food security in developing countries.
CTLGH: A global shared data biological sample resource to support productivity improvement for tropical livestock
1/10/15 → 31/03/22
3/04/17 → 31/03/18
Understanding the functional and genomic architecture of the rumen microbiome affecting performance traits in bovines
1/12/16 → 30/11/19