In this chapter, we provide an overview of the basic biophysical concepts that allow for the assessment of changes in myocardial blood oxygenation. We summarize the preclinical and clinical literature to date in the assessment of myocardial oxygenation as well as the growing literature on image-processing methods that have the capacity to enable accurate visualization and quantification of blood-oxygen-level-dependent (BOLD) signal changes in the myocardium. Finally we review the emerging methods which show promising evidence into how BOLD cardiovascular magnetic resonance (CMR) can become a reliable tool for examining ischemic heart disease in the clinical arena and conclude with a brief outlook on the future of myocardial BOLD CMR.
|Title of host publication||Cardiovascular Magnetic Resonance|
|Subtitle of host publication||A Companion to Braunwald's Heart Disease|
|Publication status||Published - 2019|