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• Selected Roche Lobe Variables - collaborative drawings: Paper Planes group exhibition curated by Andrew Mackenzie

  Robertson, E. & Kirkwood, K., 30 Sep 2013

  Research output: Non-textual form › Exhibition

• Neosensitization to allergens after resolution of allergic airways inflammation: a new role for airway dendritic cells

  Schwarze, J. & Mackenzie, K. J., 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 3, p. 283-4 2 p.

  Research output: Contribution to journal › Editorial

• CD11c(+) lung antigen presenting cells (APCs) from RSV infected mice have an enhanced ability to induce Th2, but not Th1, recall responses to allergen

  Ilchmann, A., Mackenzie, K., Fitch, P. & Schwarze, J., Dec 2011, In: Immunology . 135, p. 131-131 1 p.

  Research output: Contribution to journal › Meeting abstract

• Peptide-based immunotherapy significantly reduces the severity of disease in an adoptive transfer model of ovalbumin-induced allergic airways inflammation

  Mackenzie, K., Fitch, P., Ilchmann, A., Nowakowska, D., Anderton, S. & Schwarze, J., Dec 2011, In: Immunology . 135, p. 191-191 1 p.

  Research output: Contribution to journal › Meeting abstract

• Heligmosomoides polygyrus co-infection reduces lung immune cell responses to respiratory syncytial virus

  McFarlane, A., McSorley, H. J., Mackenzie, K. J., Fitch, P. M., Ilchmann, A., Maizels, R. M. & Schwarze, J., Sep 2012, In: Immunology . 137, p. 638-639 2 p.

  Research output: Contribution to journal › Meeting abstract

• Efficacious peptide-based immunotherapy in a model of allergic airways inflammation occurs independently of IL-10

  Mackenzie, K. J., Fitch, P. M., Nowakowska, D., Leech, M. D., McFarlane, A., Ilchmann, A., Howie, S. E. M., Schwarze, J. & Anderton, S. M., Sep 2012, In: Immunology . 137, p. 446-446 1 p.

  Research output: Contribution to journal › Meeting abstract

• Peptide immunotherapy for childhood allergy - addressing translational challenges

  Mackenzie, K. J., Anderton, S. M. & Schwarze, J., 2011, In: Clinical and translational allergy. 1, 1, p. 13

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

• Distinct T cell recognition of naturally processed and cryptic epitopes within the immunodominant 35-55 region of myelin oligodendrocyte glycoprotein

  Sweenie, C. H., Mackenzie, K. J., Rone-Orugboh, A., Liu, M. & Anderton, S. M., 2007, In: Journal of Neuroimmunology. 183, 1-2, p. 7-16 10 p.

  Research output: Contribution to journal › Article › peer-review

• Novel insights into immune and inflammatory responses to respiratory viruses

  Schwarze, J. & Mackenzie, K. J., Jan 2013, In: Thorax. 68, 1, p. 108-110 3 p.

  Research output: Contribution to journal › Review article › peer-review

• Cathelicidins induce protective inflammation and cell death and enhance host defence in murine models of pulmonary bacterial and viral infection

  Beaumont, P. E., Barlow, P. G., Mackellar, A., MacKenzie, K., Svoboda, P., Nash, A., York, I. A., Pohl, J., Gallo, R. L., Donis, R. O., Govan, J. R. & Davidson, D. J., Dec 2011, In: Immunology . 135, p. 46-46 1 p.

  Research output: Contribution to journal › Meeting abstract

• Viral respiratory tract infections and asthma in early life: cause and effect?

  Mackenzie, K. J., Anderton, S. M. & Schwarze, J., Jan 2014, In: Clinical & Experimental Allergy. 44, 1, p. 9-19 11 p.

  Research output: Contribution to journal › Literature review › peer-review

• Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

  Mackenzie, K. J., Carroll, P., Lettice, L., Tarnauskaite, Z., Reddy, K., Dix, F., Revuelta, A., Abbondati, E., Rigby, R. E., Rabe, B., Kilanowski, F., Grimes, G. R., Fluteau, A., Devenney, P. S., Hill, R. E., Reijns, M. A. M. & Jackson, A. P., 15 Apr 2016, In: EMBO Journal. 35, 8, p. 831-844 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo

  Beaumont, P. E., McHugh, B., Gwyer Findlay, E., Mackellar, A., Mackenzie, K. J., Gallo, R. L., Govan, J. R. W., Simpson, A. J. & Davidson, D. J., 2 Jun 2014, In: PLoS ONE. 9, 6, e99029.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

  Rigby, R. E., Webb, L. M., Mackenzie, K. J., Li, Y., Leitch, A., Reijns, M. A. M., Lundie, R. J., Revuelta, A., Davidson, D. J., Diebold, S., Modis, Y., MacDonald, A. S. & Jackson, A. P., 18 Mar 2014, In: EMBO Journal. 33, 6, p. 542-558 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Inhibition of eosinophil migration by lactoferrin

  Bournazou, I., Mackenzie, K. J., Duffin, R., Rossi, A. G. & Gregory, C. D., Feb 2010, In: Immunology & Cell Biology. 88, 2, p. 220-223 4 p.

  Research output: Contribution to journal › Article › peer-review

• TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism

  Harley, M. E., Murina, O., Leitch, A., Higgs, M., Bicknell, L. S., Yigit, G., Blackford, A., Zlatanou, A., Mackenzie, K. J., Reddy, K., Halachev, M., McGlasson, S., Reijns, M. A. M., Fluteau, A., Martin, C-A., Sabbioneda, S., Elcioglu, N. H., Altmuller, J., Thiele, H., Greenhalgh, L., & 10 othersChessa, L., Maghnie, M., Salim, M., Bober, M. B., Nurnberg, P., Jackson, S. P., Hurles, M. E., Wollnik, B., Stewart, G. S. & Jackson, A. P., Jan 2016, In: Nature Genetics. 48, 1, p. 36-43 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• cGAS surveillance of micronuclei links genome instability to innate immunity

  Mackenzie, K. J., Carroll, P., Martin, C-A., Murina, O., Fluteau, A., Simpson, D. J., Olova, N., Sutcliffe, H., Rainger, J. K., Leitch, A., Osborn, R. T., Wheeler, A. P., Nowotny, M., Gilbert, N., Chandra, T., Reijns, M. A. M. & Jackson, A. P., 24 Aug 2017, In: Nature. 548, 7668, p. 461–465 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis

  Kerrin, A., Fitch, P., Errington, C., Kerr, D., Waxman, L., Riding, K., McCormack, J., Mehendale, F., McSorley, H., Mackenzie, K., Wronski, S., Braun, A., Leven, R., Theilen, U. & Schwarze, J., 16 Jun 2017, In: Thorax. 72, 7, p. 620-627

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

  McFarlane, A. J., McSorley, H. J., Davidson, D. J., Fitch, P. M., Errington, C., Mackenzie, K. J., Gollwitzer, E. S., Johnston, C. J. C., MacDonald, A. S., Edwards, M. R., Harris, N. L., Marsland, B. J., Maizels, R. M. & Schwarze, J., 1 Oct 2017, In: Journal of Allergy and Clinical Immunology. 140, 4, p. 1068-1078.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

  Mackenzie, K. J., Nowakowska, D. J., Leech, M. D., McFarlane, A. J., Wilson, C., Fitch, P. M., O'Connor, R. A., Howie, S. E. M., Schwarze, J. & Anderton, S. M., 25 Feb 2014, In: Proceedings of the National Academy of Sciences (PNAS). 111, 8, p. E784-E793 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis

  The DDD Study, Wood, A. J., Vagnarelli, P. & Jackson, A. P., Oct 2016, In: Genes and Development. 30, 19, p. 2158-2172 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Combination peptide immunotherapy based on T cell epitope mapping reduces allergen-specific IgE and eosinophilia in allergic airway inflammation

  Mackenzie, K. J., Fitch, P. M., Leech, M. D., Ilchmann, A., Wilson, C., McFarlane, A., Howie, S. E., Anderton, S. M. & Schwarze, J., Mar 2013, In: Immunology . 138, 3, p. 258-268 11 p.

  Research output: Contribution to journal › Article › peer-review

• Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling

  Lepelley, A., Martin-niclós, M. J., Le Bihan, M., Marsh, J. A., Uggenti, C., Rice, G. I., Bondet, V., Duffy, D., Hertzog, J., Rehwinkel, J., Amselem, S., Boulisfane-el Khalifi, S., Brennan, M., Carter, E., Chatenoud, L., Chhun, S., Coulomb L’hermine, A., Depp, M., Legendre, M., Mackenzie, K. J., & 12 othersMarey, J., Mcdougall, C., Mckenzie, K. J., Molina, T. J., Neven, B., Seabra, L., Thumerelle, C., Wislez, M., Nathan, N., Manel, N., Crow, Y. J. & Frémond, M., 28 Jul 2020, (E-pub ahead of print) In: Journal of Experimental Medicine. 217, 11

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Runx1 deficiency protects against adverse cardiac remodeling following myocardial infarction

  McCarroll, C. S., He, W., Foote, K., Bradley, A., McGlynn, K., Vidler, F., Nixon, C., Nather, K., Fattah, C., H. Riddell, A., Bowman, P., B. Elliott, E., Bell, M., Hawksby, C., MacKenzie, S. M., Morrison, L., Terry, A., Blyth, K., L. Smith, G., W. McBride, M., & 5 othersKubin, T., Braun, T., Nicklin, S. A., Cameron, E. R. & Loughrey, C. M., 2 Jan 2018, In: Circulation. 137, 1, p. 57-70

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Mutations in the pre-replication complex cause Meier-Gorlin syndrome

  Bicknell, L. S., Bongers, E. M. H. F., Leitch, A., Brown, S., Schoots, J., Harley, M. E., Aftimos, S., Al-Aama, J. Y., Bober, M., Brown, P. A. J., van Bokhoven, H., Dean, J., Edrees, A. Y., Feingold, M., Fryer, A., Hoefsloot, L. H., Kau, N., Knoers, N. V. A. M., Mackenzie, J., Opitz, J. M., & 7 othersSarda, P., Ross, A., Temple, I. K., Toutain, A., Wise, C. A., Wright, M. & Jackson, A. P., Apr 2011, In: Nature Genetics. 43, 4, p. 356-359 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File