@article{c0c050caa14e45c9988e682954886ff6,
title = "A bioinspired, one-step total synthesis of peshawaraquinone",
abstract = "A concise synthesis of a stereochemically complex meroterpenoid, peshawaraquinone, via the unsymmetrical dimerization of its achiral precursor, dehydro-α-lapachone, is reported. Enabled by reversible oxa-6π-electrocyclizations of 2H-pyran intermediates, the base-catalyzed dimerization sets up an intramolecular (3 + 2) cycloaddition, with the formation of six stereocenters during the cascade. Combining the generation and in situ dimerization of dehydro-α-lapachone allows a one-step total synthesis of peshawaraquinone from lawsone and prenal.",
author = "{Vieira de Castro}, Tom{\'a}s and Huang, {David M.} and Sumby, {Christopher J.} and Lawrence, {Andrew L.} and George, {Jonathan H.}",
note = "Funding Information: We thank the Australian Research Council (DP200102964 and LE210100163), the University of Adelaide and the University of Edinburgh for funding this work. This research was undertaken with the assistance of resources and services from the National Computational Infrastructure (NCI), which is supported by the Australian Government. Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry.",
year = "2022",
month = dec,
day = "21",
doi = "10.1039/d2sc05377b",
language = "English",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
}