A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Chris D. Bailey, Chris E. Houlden, Gregory L. J. Bar, Guy C. Lloyd-Jones, Kevin I. Booker-Milburn*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.

Original languageEnglish
Pages (from-to)2932-2934
Number of pages3
JournalChemical Communications
Issue number28
DOIs
Publication statusPublished - 2007

Keywords

  • MULTICOMPONENT REACTIONS
  • BIGINELLI REACTION
  • CATALYST
  • DESIGN
  • UREA

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