A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Chris D. Bailey; Chris E. Houlden; Gregory L. J. Bar; Guy C. Lloyd-Jones; Kevin I. Booker-Milburn

doi:10.1039/b707361e

A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Chris D. Bailey, Chris E. Houlden, Gregory L. J. Bar, Guy C. Lloyd-Jones, Kevin I. Booker-Milburn^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.

Original language	English
Pages (from-to)	2932-2934
Number of pages	3
Journal	Chemical Communications
Issue number	28
DOIs	https://doi.org/10.1039/b707361e
Publication status	Published - 2007

Keywords / Materials (for Non-textual outputs)

MULTICOMPONENT REACTIONS
BIGINELLI REACTION
CATALYST
DESIGN
UREA

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10.1039/b707361e

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@article{b1f25a33f5a94e23b62bd3cf85fbf05d,

title = "A chemo- and regio-selective three-component dihydropyrimidinone synthesis",

abstract = "A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.",

keywords = "MULTICOMPONENT REACTIONS, BIGINELLI REACTION, CATALYST, DESIGN, UREA",

author = "Bailey, {Chris D.} and Houlden, {Chris E.} and Bar, {Gregory L. J.} and Lloyd-Jones, {Guy C.} and Booker-Milburn, {Kevin I.}",

year = "2007",

doi = "10.1039/b707361e",

language = "English",

pages = "2932--2934",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "28",

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TY - JOUR

T1 - A chemo- and regio-selective three-component dihydropyrimidinone synthesis

AU - Bailey, Chris D.

AU - Houlden, Chris E.

AU - Bar, Gregory L. J.

AU - Lloyd-Jones, Guy C.

AU - Booker-Milburn, Kevin I.

PY - 2007

Y1 - 2007

N2 - A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.

AB - A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.

KW - MULTICOMPONENT REACTIONS

KW - BIGINELLI REACTION

KW - CATALYST

KW - DESIGN

KW - UREA

U2 - 10.1039/b707361e

DO - 10.1039/b707361e

M3 - Article

SN - 1359-7345

SP - 2932

EP - 2934

JO - Chemical Communications

JF - Chemical Communications

IS - 28

ER -

A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Access to Document

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Cite this