A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

Kevin J Spears; Andrew J Roe; David L Gally

doi:10.1111/j.1574-6968.2006.00119.x

A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

Kevin J Spears, Andrew J Roe, David L Gally

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.

Original language	English
Pages (from-to)	187-202
Number of pages	16
Journal	FEMS Microbiology Letters
Volume	255
Issue number	2
DOIs	https://doi.org/10.1111/j.1574-6968.2006.00119.x
Publication status	Published - 2006

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10.1111/j.1574-6968.2006.00119.x

The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle
Gally, D.
BBSRC
1/12/03 → 31/01/07
Project: Research
The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle
Gally, D.
1/12/03 → 31/01/07
Project: Research Collaboration with external organisation

Cite this

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title = "A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis",

abstract = "This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.",

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AU - Gally, David L

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AB - This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.

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DO - 10.1111/j.1574-6968.2006.00119.x

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EP - 202

JO - FEMS Microbiology Letters

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A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

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The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle

The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle

Cite this