A guide to understanding polycystic ovary syndrome (PCOS)

W. Colin Duncan

doi:10.1136/jfprhc-2012-100505

A guide to understanding polycystic ovary syndrome (PCOS)

W. Colin Duncan^*

^*Corresponding author for this work

Research output: Contribution to journal › Literature review › peer-review

Abstract

Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting women of reproductive age. Some 20% of women will have polycystic ovaries on an ultrasound scan and around 7% of women have the additional clinical or biochemical features of PCOS. As a complex multisystem disorder its background can be confusing to understand. They key feature, however, is an increased production of androgen by the ovaries. This review uses ovarian biology to describe a strategy to aid understanding and explanation of PCOS. This framework can be also be used to teach about PCOS and to inform different approaches to its management.

Original language	English
Pages (from-to)	217-225
Number of pages	9
Journal	Journal of Family Planning and Reproductive Health Care
Volume	40
Issue number	3
DOIs	https://doi.org/10.1136/jfprhc-2012-100505
Publication status	Published - Jul 2014

Keywords / Materials (for Non-textual outputs)

INSULIN-SENSITIZING DRUGS
BODY-MASS INDEX
LUTEINIZING-HORMONE
OVULATION INDUCTION
ANDROGEN EXCESS
WEIGHT-LOSS
IN-VITRO
WOMEN
METFORMIN
MANAGEMENT

Access to Document

10.1136/jfprhc-2012-100505

Polycystic ovary syndrome (PCOS): manipulation of hormonal metabolic and ovarian phenotypes using a developmental model
Duncan, C.
MRC
1/07/10 → 31/12/13
Project: Research

Cite this

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title = "A guide to understanding polycystic ovary syndrome (PCOS)",

abstract = "Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting women of reproductive age. Some 20% of women will have polycystic ovaries on an ultrasound scan and around 7% of women have the additional clinical or biochemical features of PCOS. As a complex multisystem disorder its background can be confusing to understand. They key feature, however, is an increased production of androgen by the ovaries. This review uses ovarian biology to describe a strategy to aid understanding and explanation of PCOS. This framework can be also be used to teach about PCOS and to inform different approaches to its management.",

keywords = "INSULIN-SENSITIZING DRUGS, BODY-MASS INDEX, LUTEINIZING-HORMONE, OVULATION INDUCTION, ANDROGEN EXCESS, WEIGHT-LOSS, IN-VITRO, WOMEN, METFORMIN, MANAGEMENT",

author = "Duncan, {W. Colin}",

year = "2014",

month = jul,

doi = "10.1136/jfprhc-2012-100505",

language = "English",

volume = "40",

pages = "217--225",

journal = "Journal of Family Planning and Reproductive Health Care",

issn = "1471-1893",

publisher = "BMJ Publishing Group",

number = "3",

}

TY - JOUR

T1 - A guide to understanding polycystic ovary syndrome (PCOS)

AU - Duncan, W. Colin

PY - 2014/7

Y1 - 2014/7

N2 - Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting women of reproductive age. Some 20% of women will have polycystic ovaries on an ultrasound scan and around 7% of women have the additional clinical or biochemical features of PCOS. As a complex multisystem disorder its background can be confusing to understand. They key feature, however, is an increased production of androgen by the ovaries. This review uses ovarian biology to describe a strategy to aid understanding and explanation of PCOS. This framework can be also be used to teach about PCOS and to inform different approaches to its management.

AB - Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting women of reproductive age. Some 20% of women will have polycystic ovaries on an ultrasound scan and around 7% of women have the additional clinical or biochemical features of PCOS. As a complex multisystem disorder its background can be confusing to understand. They key feature, however, is an increased production of androgen by the ovaries. This review uses ovarian biology to describe a strategy to aid understanding and explanation of PCOS. This framework can be also be used to teach about PCOS and to inform different approaches to its management.

KW - INSULIN-SENSITIZING DRUGS

KW - BODY-MASS INDEX

KW - LUTEINIZING-HORMONE

KW - OVULATION INDUCTION

KW - ANDROGEN EXCESS

KW - WEIGHT-LOSS

KW - IN-VITRO

KW - WOMEN

KW - METFORMIN

KW - MANAGEMENT

U2 - 10.1136/jfprhc-2012-100505

DO - 10.1136/jfprhc-2012-100505

M3 - Literature review

SN - 1471-1893

VL - 40

SP - 217

EP - 225

JO - Journal of Family Planning and Reproductive Health Care

JF - Journal of Family Planning and Reproductive Health Care

IS - 3

ER -

A guide to understanding polycystic ovary syndrome (PCOS)

Abstract

Keywords / Materials (for Non-textual outputs)

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Polycystic ovary syndrome (PCOS): manipulation of hormonal metabolic and ovarian phenotypes using a developmental model

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