A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

Liyun Zhang, Jun Cheng Er, Hao Jiang, Xin Li, Zhaofeng Luo, Thomas Ramezani, Yi Feng, Mui Kee Tang, Young-Tae Chang, Marc Vendrell

Research output: Contribution to journalArticlepeer-review

Abstract

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

Original languageEnglish
JournalChemical Communications
DOIs
Publication statusPublished - 4 Mar 2016

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