A life course approach to cognitive reserve: A model for cognitive aging and development?

M Richards, I J Deary

Research output: Contribution to journalArticlepeer-review

Abstract

The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.

Original languageEnglish
Pages (from-to)617-622
Number of pages6
JournalAnnals of Indian Academy of Neurology
Volume58
Issue number4
DOIs
Publication statusPublished - Oct 2005

Keywords

  • SCOTTISH MENTAL SURVEY
  • ALZHEIMERS-DISEASE
  • APOLIPOPROTEIN-E
  • BIRTH-WEIGHT
  • OLD-AGE
  • INTELLECTUAL-DEVELOPMENT
  • DEGENERATIVE CHANGES
  • HEAD CIRCUMFERENCE
  • ELDERLY SUBJECTS
  • EPISODIC MEMORY

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