A linkage map for the hybridising toads Bombina bombina and B. variegata (Anura: Discoglossidae): Discoglossidae)

B. Nürnberger, S. Hofman, B. Förg-Brey, G. Praetzel, A. Maclean, J.M. Szymura, C.M. Abbott, N.H. Barton

Research output: Contribution to journalArticlepeer-review

Abstract

Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae). Adaptations to permanent and ephemeral breeding habitats, respectively, have shaped numerous phenotypic differences between the taxa. All of these are, in principle, candidates for a genetic dissection via QTL mapping. We present here a linkage map of 28 codominant and 10 dominant markers in the Bombina genome. In an F2 cross, markers that were mainly microsatellites, SSCPs or allozymes were mapped to 20 linkage groups. Among the 40 isolated CA microsatellites, we noted a preponderance of compound and frequently interleaved CA-TA repeats as well as a striking polarity at the 5' end of the repeats.
Original languageEnglish
Pages (from-to)136-142
Number of pages7
JournalHeredity
Volume91
Issue number2
DOIs
Publication statusPublished - 1 Aug 2003

Keywords

  • Animals
  • Anura
  • Chromosome Mapping
  • Crosses, Genetic
  • Female
  • Genetic Markers
  • Hybridization, Genetic
  • Isoenzymes
  • Male
  • Microsatellite Repeats
  • Polymorphism, Single-Stranded Conformational
  • Species Specificity

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