A Microbiome Analysis of Equine Peripheral Dental Caries using Next Generation Sequencing

Dewi Borkent; Richard Reardon; Gerry McLachlan; Laura Glendinning; Paddy Dixon

doi:10.1111/evj.13126

A Microbiome Analysis of Equine Peripheral Dental Caries using Next Generation Sequencing

Dewi Borkent, Richard Reardon, Gerry McLachlan, Laura Glendinning, Paddy Dixon

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Background: Although, peripheral caries (PC) affects almost half of UK horses, no comprehensive microbiological study has been performed on this disorder. Because a high proportion of oral bacteria cannot
be conventionally cultured, a molecular microbiological technique such as Next Generation Sequencing are required to examine the complex oral bacteria community.

Objectives: To identify the microbiota involved in equine PC, including comparing microbiota at the more commonly and severely affected three caudal cheek teeth with the less commonly affected three rostral cheek
teeth

Original language	English
Journal	Equine Veterinary Journal
Early online date	21 Apr 2019
DOIs	https://doi.org/10.1111/evj.13126
Publication status	E-pub ahead of print - 21 Apr 2019

Keywords / Materials (for Non-textual outputs)

horse
dental disease
dental caries
peripheral caries
microbiology
molecular microbiology

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10.1111/evj.13126

05_09_2018_article microbiology PMD DB (1)Accepted author manuscript, 90.8 KB

Gerry McLachlan
- Gerry.McLachlaned.acuk
- Royal (Dick) School of Veterinary Studies - Group Leader/Senior Research Fellow
- Edinburgh Imaging
Person: Academic: Research Active

Cite this

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title = "A Microbiome Analysis of Equine Peripheral Dental Caries using Next Generation Sequencing",

abstract = "Background: Although, peripheral caries (PC) affects almost half of UK horses, no comprehensive microbiological study has been performed on this disorder. Because a high proportion of oral bacteria cannot be conventionally cultured, a molecular microbiological technique such as Next Generation Sequencing are required to examine the complex oral bacteria community. Objectives: To identify the microbiota involved in equine PC, including comparing microbiota at the more commonly and severely affected three caudal cheek teeth with the less commonly affected three rostral cheek teeth",

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AU - Borkent, Dewi

AU - Reardon, Richard

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AU - Glendinning, Laura

AU - Dixon, Paddy

PY - 2019/4/21

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AB - Background: Although, peripheral caries (PC) affects almost half of UK horses, no comprehensive microbiological study has been performed on this disorder. Because a high proportion of oral bacteria cannot be conventionally cultured, a molecular microbiological technique such as Next Generation Sequencing are required to examine the complex oral bacteria community. Objectives: To identify the microbiota involved in equine PC, including comparing microbiota at the more commonly and severely affected three caudal cheek teeth with the less commonly affected three rostral cheek teeth

KW - horse

KW - dental disease

KW - dental caries

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KW - microbiology

KW - molecular microbiology

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A Microbiome Analysis of Equine Peripheral Dental Caries using Next Generation Sequencing

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Keywords / Materials (for Non-textual outputs)

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Gerry McLachlan

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