A Model of Regulatory Burden in Technology Diffusion: The Case of Plant-Derived Vaccines

David Castle, Kira Kumagai, Celine Berard, Martin Cloutier, Richard Gold

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Plant-derived vaccines may soon displace conventional vaccines. Assuming there are no major technological barriers undermining the feasibility of this innovative technology, it is worthwhile to generate quantitative models of regulatory burden of producing and diffusing plant-derived vaccines in industrialized and developing countries. A dynamic simulation model of technology diffusion—and the data to populate it—has been generated for studying regulatory barriers in the diffusion of plant-derived vaccines. The role of regulatory burden is evaluated for a variety of scenarios in which plant-derived vaccines are produced and diffused. This model relates the innovative and conventional vaccine technologies and the effects of the impact of the uptake of the innovative technology on mortality and morbidity. This case study demonstrates how dynamic simulation models can be used to assess the long-term potential impact of novel technologies in terms of a variety of socio-economic indicators.
Original languageEnglish
Pages (from-to)108-118
JournalThe Journal of Agrobiotechnology
Issue number1
Publication statusPublished - 2009

Keywords / Materials (for Non-textual outputs)

  • dynamic simulation model
  • plant-derived vaccines
  • regulatory burden
  • technology transfer
  • vaccines


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