@article{9099f50d46cc4770b36e77b50af0d47a,
title = "A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging",
abstract = "We report a platform combining multicomponent reaction synthesis and automated cell-based screening to develop biocompatible NIR-BODIPY fluorophores. From a library of over 60 fluorophores, we optimised compound NIRBD-62c as a multimodal probe with suitable properties for STED super-resolution and fluorescence lifetime imaging. Furthermore, we employed NIRBD-62c for imaging trafficking inside cells and to examine how pharmacological inhibitors can alter the vesicular traffic between intracellular compartments and the plasma membrane.",
author = "Antonio Fernandez and Nicola Kielland and Ashraff Makda and Carragher, {Neil O.} and Gonz{\'a}lez-garc{\'i}a, {M. Carmen} and Laura Espinar-barranco and Gonz{\'a}lez-vera, {Juan A.} and Angel Orte and Rodolfo Lavilla and Marc Vendrell",
note = "Funding Information: A. F. acknowledges the support of Fundaci{\'o}n S{\'e}neca for the Saavedra Fajardo Grant (21124/SF/19). A. O. and J. A. G. V. acknowledge the grant PID2020-114256RB-I00 from MCIN/AEI/10.13039/501100011033. R. L. acknowledges funding from the Ministry of Science and Innovation-Spain (PID2019-107991RB-I00). M. V. acknowledges funding from an ERC Consolidator Grant (771443) and the Royal Society (RG160289). Publisher Copyright: {\textcopyright} 2022 RSC.",
year = "2022",
month = aug,
day = "25",
doi = "10.1039/D2CB00168C",
language = "English",
journal = "RSC Chemical Biology",
issn = "2633-0679",
publisher = "Royal Society of Chemistry",
}