A multisystemic Acanthamoeba infection in a dog in Tenerife, Canary Islands, Spain

María Valladares, María Reyes-Batlle, Inmaculada Mora-Peces, Carmen M Martín-Navarro, Atteneri López-Arencibia, Alexis Dorta-Gorrín, Estefanía Comyn-Afonso, Enrique Martínez-Carretero, Sutherland K Maciver, José E Piñero, Basilio Valladares, Jacob Lorenzo-Morales

Research output: Contribution to journalComment/debatepeer-review

Abstract / Description of output

A 22-month-old male Spanish water dog was hospitalized after its physical examination revealed fever and movement difficulty. After 24h, the dog was found to have a high fever (39.5 °C) and was treated empirically with doxycycline/ciprofloxacin. At 48 h, after submission the fever rose to 41 °C and the animal presented with a stiff neck and dehydration. Peripheral blood and cerebrospinal fluid (CSF) were sampled and trophozoites with an Acanthamoeba-like morphology were observed in the CSF. PCR specific for Acanthamoeba, Naegleria fowleri and Balamuthia mandrillaris were performed and the CSF sample found positive for Acanthamoeba. Lungs, kidney, liver and spleen samples were collected post mortem. All collected organ samples were positive for Acanthamoeba by PCR, thus confirming a multisystemic infection. Water samples taken at a suspected site of infection yielded an almost identical PCR fragment to those of the clinical samples, indicating that this was probably where the infection originated. This is the first report of a fatal case of Acanthamoeba disseminated infection in a dog in Spain.

Original languageEnglish
Pages (from-to)707-11
Number of pages5
JournalVeterinary Parasitology
Volume205
Issue number3-4
DOIs
Publication statusPublished - 15 Oct 2014

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