TY - JOUR
T1 - A new family of fullerene derivatives
T2 - Fullerene-curcumin conjugates for biological and photovoltaic applications
AU - Castro, Edison
AU - Cerón, Maira R.
AU - Garcia, Andrea Hernandez
AU - Kim, Quentin
AU - Etcheverry-Berríos, Alvaro
AU - Morel, Mauricio J.
AU - Díaz-Torres, Raúl
AU - Qian, Wenjie
AU - Martinez, Zachary
AU - Mendez, Lois
AU - Perez, Frank
AU - Santoyo, Christy A.
AU - Gimeno-Muñoz, Raquel
AU - Esper, Ronda
AU - Gutierrez, Denisse A.
AU - Varela-Ramirez, Armando
AU - Aguilera, Renato J.
AU - Llano, Manuel
AU - Soler, Monica
AU - Aliaga-Alcalde, Núria
AU - Echegoyen, Luis
N1 - Funding Information:
The authors thank the US National Science Foundation (NSF) for the generous support of this work under the NSF-PREM program DMR 1205302 and CHE-1801317 (to L. E.). The Robert A. Welch Foundation is also gratefully acknowledged for an endowed chair to L. E. (Grant AH-0033). MS acknowledges support through the FONDECYT Grant Number 1161775, 3170509. AEB thanks Conicyt PFCHA 21140734 for a PhD scholarship. The work of N. A.-A. has been supported by the Spanish Government by the project MAT2016-77852-C2-1-R and acknowledge the ‘‘Severo Ochoa’’ Program for Centres of Excellence in R&D (SEV-2015-0496). N. A.-A. and W. Q. thanks to the Generalitat de Catalunya, FI-DGR grant 2014. R. D.-T. thanks to the Fundació Montcelimar. A. E. B., M. S and N. A.-A. thank to the CSIC (project iCOOP20162). ML thanks the National Institute of General Medical Sciences (NIGMS) Grant Number 5 SC1 AI098238-02 and the National Institutes of Health (NIH). The Cytometry, Screening and Imaging Core Facility-BBRC-UTEP that was used in this work was supported by the National Institute on Minority Health and Health Disparities (NIMHD) through a Research Centers for Minority Institutions (RCMI) grant [5G12MD007592] a component of NIH. We also thank Dr Narayan for helping us with the antiradical experiments.
Publisher Copyright:
© 2019 The Royal Society of Chemistry.
PY - 2018/12/13
Y1 - 2018/12/13
N2 - The synthesis and characterization of a family of [60]fullerocurcuminoids obtained via Bingel reactions is reported. The new C 60 derivatives include curcumin and curcuminoids with a variety of end groups. Preliminary biological experiments show the potential activity of the compound containing a curcumin addend, which exhibits moderate anti-HIV-1 and radical scavenger properties, but no anti-cancer activity. In addition, the new fullerocurcuminoids exhibit HOMO/LUMO energy levels that are reasonably matched with those of perovskites and when they were tested in perovskite solar cells (PSCs) as the electron transporting material (ETM), photoconversion efficiencies ranging from 14.04-14.95% were obtained, whereas a value of 16.23% was obtained for [6,6]-phenyl-C 61 -butyric acid methyl ester (PC 61 BM) based devices.
AB - The synthesis and characterization of a family of [60]fullerocurcuminoids obtained via Bingel reactions is reported. The new C 60 derivatives include curcumin and curcuminoids with a variety of end groups. Preliminary biological experiments show the potential activity of the compound containing a curcumin addend, which exhibits moderate anti-HIV-1 and radical scavenger properties, but no anti-cancer activity. In addition, the new fullerocurcuminoids exhibit HOMO/LUMO energy levels that are reasonably matched with those of perovskites and when they were tested in perovskite solar cells (PSCs) as the electron transporting material (ETM), photoconversion efficiencies ranging from 14.04-14.95% were obtained, whereas a value of 16.23% was obtained for [6,6]-phenyl-C 61 -butyric acid methyl ester (PC 61 BM) based devices.
U2 - 10.1039/c8ra08334g
DO - 10.1039/c8ra08334g
M3 - Article
AN - SCOPUS:85058872196
VL - 8
SP - 41692
EP - 41698
JO - RSC Advances
JF - RSC Advances
SN - 2046-2069
IS - 73
ER -