A new mouse model to explore therapies for preeclampsia

Abdulwahab Ahmed; Jameel Singh; Ysodra Khan; Surya V Seshan; Guillermina Girardi

doi:10.1371/journal.pone.0013663

A new mouse model to explore therapies for preeclampsia

Abdulwahab Ahmed, Jameel Singh, Ysodra Khan, Surya V Seshan, Guillermina Girardi

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Pre-eclampsia, a pregnancy-specific multisystemic disorder is a leading cause of maternal and perinatal mortality and morbidity. This syndrome has been known to medical science since ancient times. However, despite considerable research, the cause/s of preeclampsia remain unclear, and there is no effective treatment. Development of an animal model that recapitulates this complex pregnancy-related disorder may help to expand our understanding and may hold great potential for the design and implementation of effective treatment.

Original language	English
Article number	e13663
Pages (from-to)	-
Number of pages	9
Journal	PLoS ONE
Volume	5
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0013663
Publication status	Published - 2010

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Ahmed 2010Submitted manuscript, 2.08 MB

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AB - Pre-eclampsia, a pregnancy-specific multisystemic disorder is a leading cause of maternal and perinatal mortality and morbidity. This syndrome has been known to medical science since ancient times. However, despite considerable research, the cause/s of preeclampsia remain unclear, and there is no effective treatment. Development of an animal model that recapitulates this complex pregnancy-related disorder may help to expand our understanding and may hold great potential for the design and implementation of effective treatment.

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A new mouse model to explore therapies for preeclampsia

Abstract

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