A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

R J Roberts, M Belfort, T Bestor, A S Bhagwat, T A Bickle, J Bitinaite, R M Blumenthal, S K Degtyarev, D T F Dryden, K Dybvig, K Firman, E S Gromova, R I Gumport, S E Halford, S Hattman, J Heitman, D P Hornby, A Janulaitis, A Jeltsch, J JosephsenA Kiss, T R Klaenhammer, I Kobayashi, H M Kong, D H Kruger, S Lacks, M G Marinus, M Miyahara, R D Morgan, N E Murray, V Nagaraja, A Piekarowicz, A Pingoud, E Raleigh, D N Rao, N Reich, V E Repin, E U Selker, P C Shaw, D C Stein, B L Stoddard, W Szybalski, T A Trautner, J L Van Etten, J M B Vitor, G G Wilson, S Y Xu

Research output: Contribution to journalArticlepeer-review


A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many different Type II enzymes now identified and provides a system for naming the putative genes found by sequence analysis of microbial genomes.

Original languageEnglish
Pages (from-to)1805-1812
Number of pages8
JournalNucleic Acids Research
Issue number7
Publication statusPublished - 1 Apr 2003

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