A novel framework to build saliva-based DNA methylation biomarkers: quantifying systemic chronic inflammation as a case study

Search results

• Active

  Exploiting genomic approaches to identify the environmental basis of depression

  McIntosh, A. (Principal Investigator)

  Wellcome Trust (Rcl)

  1/06/21 → 31/05/26

  Project: Research

  • DNA Methylation 100%
  • Major Depressive Disorder 56%
  • Epigenetics 43%
  • Genetics 37%
  • Mental Health 37%
• Finished

  Generation Scotland: NextGenScot

  Porteous, D. (Principal Investigator), Deary, I. (Co-investigator), Hayward, C. (Co-investigator), McIntosh, A. (Co-investigator) & Sudlow, C. (Co-investigator)

  UK-based charities

  1/11/19 → 31/10/24

  Project: Research

  • Mental Health 100%
  • COVID-19 86%
  • Genetics 80%
  • Genome-Wide Association Study 63%
  • DNA Methylation 59%

• Using Multiple Data Sources to Stratify Depression and Identify More Effective Drug Treatments for the Disorder

  Howard, D. (Principal Investigator)

  Non-EU-based charities

  15/01/19 → 14/01/23

  Project: Research

  • DNA Methylation 100%
  • Epigenetics 52%
  • Methylome 33%
  • Ensemble Model 33%
  • Predictive Performance 33%

• Stratifying Resilience and Depression Longitudinally

  McIntosh, A. (Principal Investigator), Deary, I. (Co-investigator), Evans, K. (Co-investigator), Haley, C. (Co-investigator) & Porteous, D. (Co-investigator)

  UK-based charities

  1/01/15 → 30/06/21

  Project: Research

  • Major Depressive Disorder 100%
  • Genetics 88%
  • Genome-Wide Association Study 73%
  • DNA Methylation 63%
  • Epigenetics 38%

• Generation Scotland

  Porteous, D. (Principal Investigator)

  UK central government bodies/local authorities, health and hospital authorities

  1/04/11 → 31/03/14

  Project: Research

  • Genetics 100%
  • Genome-Wide Association Study 76%
  • DNA Methylation 58%
  • Major Depressive Disorder 52%
  • Family Health 46%

• Genetic Health 21st Century

  Porteous, D. (Principal Investigator), Laurie, G. (Co-investigator) & Tait, J. (Co-investigator)

  UK central government bodies/local authorities, health and hospital authorities

  1/10/03 → 31/08/07

  Project: Research

  • Genetics 100%
  • Genome-Wide Association Study 86%
  • Major Depressive Disorder 63%
  • DNA Methylation 55%
  • Family Health 47%