A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

Maha Al-Thani; Mary Goodwin-Trotman; Steven  Bell; Krushangi Patel; Lauren K Fleming; Catheline Vilain; Marc Abramowicz; Stuart M Allan; Tao Wang; M Zameel Cader; Karen Horsburgh; Tom  Van Agtmael; Sanjay Sinha; Hugh S Markus; Alessandra Granata

doi:10.1016/j.stemcr.2023.10.014

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

Maha Al-Thani, Mary Goodwin-Trotman, Steven Bell, Krushangi Patel, Lauren K Fleming, Catheline Vilain, Marc Abramowicz, Stuart M Allan, Tao Wang, M Zameel Cader, Karen Horsburgh, Tom Van Agtmael, Sanjay Sinha, Hugh S Markus, Alessandra Granata

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2386-2399
Journal	Stem Cell Reports
Volume	18
Issue number	12
DOIs	https://doi.org/10.1016/j.stemcr.2023.10.014
Publication status	Published - 12 Dec 2023

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Al-Thani, M., Goodwin-Trotman, M., Bell, S., Patel, K., Fleming, L. K., Vilain, C., Abramowicz, M., Allan, S. M., Wang, T., Cader, M. Z., Horsburgh, K., Van Agtmael, T., Sinha, S., Markus, H. S., & Granata, A. (2023). A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases. Stem Cell Reports, 18(12), 2386-2399. https://doi.org/10.1016/j.stemcr.2023.10.014

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title = "A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases",

author = "Maha Al-Thani and Mary Goodwin-Trotman and Steven Bell and Krushangi Patel and Fleming, {Lauren K} and Catheline Vilain and Marc Abramowicz and Allan, {Stuart M} and Tao Wang and Cader, {M Zameel} and Karen Horsburgh and {Van Agtmael}, Tom and Sanjay Sinha and Markus, {Hugh S} and Alessandra Granata",

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doi = "10.1016/j.stemcr.2023.10.014",

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Al-Thani, M, Goodwin-Trotman, M, Bell, S, Patel, K, Fleming, LK, Vilain, C, Abramowicz, M, Allan, SM, Wang, T, Cader, MZ, Horsburgh, K, Van Agtmael, T, Sinha, S, Markus, HS & Granata, A 2023, 'A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases', Stem Cell Reports, vol. 18, no. 12, pp. 2386-2399. https://doi.org/10.1016/j.stemcr.2023.10.014

TY - JOUR

T1 - A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

AU - Al-Thani, Maha

AU - Goodwin-Trotman, Mary

AU - Bell, Steven

AU - Patel, Krushangi

AU - Fleming, Lauren K

AU - Vilain, Catheline

AU - Abramowicz, Marc

AU - Allan, Stuart M

AU - Wang, Tao

AU - Cader, M Zameel

AU - Horsburgh, Karen

AU - Van Agtmael, Tom

AU - Sinha, Sanjay

AU - Markus, Hugh S

AU - Granata, Alessandra

PY - 2023/12/12

Y1 - 2023/12/12

U2 - 10.1016/j.stemcr.2023.10.014

DO - 10.1016/j.stemcr.2023.10.014

M3 - Article

SN - 2213-6711

VL - 18

SP - 2386

EP - 2399

JO - Stem Cell Reports

JF - Stem Cell Reports

IS - 12

ER -