A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3

K Hess, S H Alzahrani, M Mathai, V Schroeder, A M Carter, G Howell, T Koko, M W J Strachan, J F Price, K A Smith, P J Grant, R A Ajjan

Research output: Contribution to journalArticlepeer-review

Abstract

Impaired fibrin clot lysis is a key abnormality in diabetes and complement C3 is one protein identified in blood clots. This work investigates the mechanistic pathways linking C3 and hypofibrinolysis in diabetes using ex vivo/in vitro studies.
Original languageEnglish
Pages (from-to)1103-13
Number of pages11
JournalDiabetologia
Volume55
Issue number4
DOIs
Publication statusPublished - 2012

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