A novel S-nitrosothiol causes prolonged and selective inhibition of platelet adhesion at sites of vascular injury

Research output: Contribution to journalArticlepeer-review

Abstract

Platelet adhesion to areas of endothelial denudation following angioplasty is an important factor contributing to the limitations of this technique. Lipophilic S-nitrosothiols like S-nitroso-N-valerylpenicillamine (SNVP) are novel nitric oxide (NO) donor drugs with anti-platelet and vasodilator properties that are selective for areas of endothelial denudation. Here we assess the inhibitory effect of SNVP on platelet adhesion to angioplastied rabbit carotid arteries.
Original languageEnglish
Pages (from-to)853-60
Number of pages8
JournalCardiovascular Research
Volume57
Issue number3
DOIs
Publication statusPublished - 1 Mar 2003

Fingerprint

Dive into the research topics of 'A novel S-nitrosothiol causes prolonged and selective inhibition of platelet adhesion at sites of vascular injury'. Together they form a unique fingerprint.

Cite this