A proposed nomenclature for cell wall proteins of Clostridium difficile

Robert P. Fagan, Claire Janoir, Anne Collignon, Paola Mastrantonio, Ian R. Poxton, Neil F. Fairweather*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Strains of Clostridium difficile produce a number of surface-localized proteins, including the Slayer proteins (SLPs) and other proteins that have suspected roles in pathogenesis. During the Third International C. difficile Symposium (Bled, Slovenia, September 2010) discussions were held on standardization of nomenclature. Gene designations were proposed for the large family of cell wall proteins that are paralogues of the SLP and contain putative cell wall binding motifs. This paper summarizes the agreed nomenclature, which we hope will be used by research groups currently active in the field.

Original languageEnglish
Pages (from-to)1225-1228
Number of pages4
JournalJournal of Medical Microbiology
Volume60
Issue number8
DOIs
Publication statusPublished - Aug 2011
Event3rd International Clostridium Difficile Symposium - Bled, Slovenia
Duration: 22 Sep 201024 Sep 2010

Keywords

  • GENES
  • GENOME
  • PURIFICATION
  • SURFACE-LAYER PROTEINS
  • INFECTION
  • TOXIN-B
  • REGULAR ARRAY

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