A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis

Eric W F W Alton, A. Christopher Boyd, Seng H. Cheng, Steve Cunningham, Jane C. Davies, Deborah R. Gill, Uta Griesenbach, Tracy Higgins, Stephen C. Hyde, J. Alastair Innes, Gordon D. Murray, David J. Porteous

Research output: Contribution to journalArticlepeer-review

Abstract

The UK Cystic Fibrosis Gene Therapy Consortium has been working towards clinical gene therapy for patients with cystic fibrosis for several years. We have recently embarked on a large, multi-dose clinical trial of a nonviral, liposome-based formulation powered for the first time to detect clinical benefit. The article describes the details of the protocol.

Original languageEnglish
Pages (from-to)1075-1077
Number of pages3
JournalThorax
Volume68
Issue number11
DOIs
Publication statusPublished - 1 Nov 2013

Fingerprint Dive into the research topics of 'A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis'. Together they form a unique fingerprint.

Cite this