A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals

Martin Fisher, Graeme J Moyle, Mohsen Shahmanesh, Chloe Orkin, Margaret Kingston, Edmund Wilkins, Jacqueline Ewan, Hui Liu, Ramin Ebrahimi, Geraldine Reilly, SWEET (Simplification With Easier Emtricitabine Tenofovir) group UK, Clifford Leen

Research output: Contribution to journalArticlepeer-review

Abstract

Long-term antiretroviral therapy dramatically reduces HIV-related morbidity and mortality but is also associated with metabolic and morphological changes and requires high levels of adherence.
Original languageEnglish
Pages (from-to)562-8
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes
Volume51
Issue number5
DOIs
Publication statusPublished - 15 Aug 2009

Keywords

  • Adenine
  • Adipose Tissue
  • Adult
  • Aged
  • Anti-HIV Agents
  • Benzoxazines
  • Deoxycytidine
  • Extremities
  • Female
  • HIV Infections
  • HIV-1
  • HIV-Associated Lipodystrophy Syndrome
  • Humans
  • Lamivudine
  • Lipids
  • Male
  • Middle Aged
  • Organophosphonates
  • Young Adult
  • Zidovudine

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