A randomized cross-over study of the metabolic and hormonal responses following two preoperative conditioning drinks

Sherif Awad, Kenneth C H Fearon, Ian A Macdonald, Dileep N Lobo

Research output: Contribution to journalArticlepeer-review

Abstract

Preoperative conditioning with carbohydrate-based drinks attenuates postoperative insulin resistance and leads to clinical benefits. The use of metabolic conditioning agents such as glutamine and antioxidants, in addition to carbohydrate, may benefit patients undergoing major surgery, because glutamine and antioxidant supplementation have been shown to improve gastrointestinal perfusion, immune function, morbidity, and gluco-metabolic control in critically ill patients. We investigated the postprandial responses after ingestion of a clear carbohydrate drink (CCD) containing 50 g of carbohydrate (preOp, Nutricia, Trowbridge, UK) and that of another drink containing 50 g of carbohydrate, 15 g of glutamine, and antioxidants (ONS; Fresenius Kabi, Bad Homburg, Germany).
Original languageEnglish
Pages (from-to)938-42
Number of pages5
JournalNutrition
Volume27
Issue number9
DOIs
Publication statusPublished - 2011

Keywords

  • Adolescent
  • Adult
  • Antioxidants
  • Beverages
  • Blood Glucose
  • Body Mass Index
  • Cross-Over Studies
  • Dietary Carbohydrates
  • Double-Blind Method
  • Fasting
  • Glutamine
  • Humans
  • Insulin
  • Male
  • Postprandial Period
  • Preoperative Care
  • Young Adult

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