A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I

G TEASDALE, Nathan W BAILEY, A BELL, J GRAY, R GULLAN, O HEISKANAN, PV MARKS, H MARSH, DA MENDELOW, G MURRAY, J OHMAN, G QUAGHEBEUR, J SINAR, A SKENE, G TEASDALE, A WATERS

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the efficacy of nimodipine in severely head-injured patients in a randomized study. Of 176 patients who received nimodipine, 2 mg/h iv for 2 day, 53% had a favorable outcome (moderate or good recovery). Of 175 control patients, 49% had a favorable outcome. This difference was not statistically significant buf does not exclude the possibility that a study of a larger number of patients could show a clinically useful benefit.

Original languageEnglish
Pages (from-to)S545-S550
Number of pages6
JournalJournal of Neurotrauma
Volume9
Publication statusPublished - May 1992
Event9TH ANNUAL MEETING OF THE NEUROTRAUMA SOC - NEW ORLEANS, Lao People's Democratic Republic
Duration: 9 Nov 199110 Nov 1991

Keywords

  • SUBARACHNOID HEMORRHAGE
  • PRETREATMENT

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