A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I

G TEASDALE; Nathan W BAILEY; A BELL; J GRAY; R GULLAN; O HEISKANAN; PV MARKS; H MARSH; DA MENDELOW; G MURRAY; J OHMAN; G QUAGHEBEUR; J SINAR; A SKENE; G TEASDALE; A WATERS

A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I

G TEASDALE, Nathan W BAILEY, A BELL, J GRAY, R GULLAN, O HEISKANAN, PV MARKS, H MARSH, DA MENDELOW, G MURRAY, J OHMAN, G QUAGHEBEUR, J SINAR, A SKENE, G TEASDALE, A WATERS

Deanery of Molecular, Genetic and Population Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

We studied the efficacy of nimodipine in severely head-injured patients in a randomized study. Of 176 patients who received nimodipine, 2 mg/h iv for 2 day, 53% had a favorable outcome (moderate or good recovery). Of 175 control patients, 49% had a favorable outcome. This difference was not statistically significant buf does not exclude the possibility that a study of a larger number of patients could show a clinically useful benefit.

Original language	English
Pages (from-to)	S545-S550
Number of pages	6
Journal	Journal of Neurotrauma
Volume	9
Publication status	Published - May 1992
Event	9TH ANNUAL MEETING OF THE NEUROTRAUMA SOC - NEW ORLEANS, Lao People's Democratic Republic Duration: 9 Nov 1991 → 10 Nov 1991

Keywords

SUBARACHNOID HEMORRHAGE
PRETREATMENT

Cite this

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title = "A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I",

abstract = "We studied the efficacy of nimodipine in severely head-injured patients in a randomized study. Of 176 patients who received nimodipine, 2 mg/h iv for 2 day, 53% had a favorable outcome (moderate or good recovery). Of 175 control patients, 49% had a favorable outcome. This difference was not statistically significant buf does not exclude the possibility that a study of a larger number of patients could show a clinically useful benefit.",

keywords = "SUBARACHNOID HEMORRHAGE, PRETREATMENT",

author = "G TEASDALE and BAILEY, {Nathan W} and A BELL and J GRAY and R GULLAN and O HEISKANAN and PV MARKS and H MARSH and DA MENDELOW and G MURRAY and J OHMAN and G QUAGHEBEUR and J SINAR and A SKENE and G TEASDALE and A WATERS",

year = "1992",

month = may,

language = "English",

volume = "9",

pages = "S545--S550",

journal = "Journal of Neurotrauma",

issn = "0897-7151",

publisher = "Mary Ann Liebert Inc.",

note = "9TH ANNUAL MEETING OF THE NEUROTRAUMA SOC ; Conference date: 09-11-1991 Through 10-11-1991",

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TY - JOUR

T1 - A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I

AU - TEASDALE, G

AU - BAILEY, Nathan W

AU - BELL, A

AU - GRAY, J

AU - GULLAN, R

AU - HEISKANAN, O

AU - MARKS, PV

AU - MARSH, H

AU - MENDELOW, DA

AU - MURRAY, G

AU - OHMAN, J

AU - QUAGHEBEUR, G

AU - SINAR, J

AU - SKENE, A

AU - TEASDALE, G

AU - WATERS, A

PY - 1992/5

Y1 - 1992/5

N2 - We studied the efficacy of nimodipine in severely head-injured patients in a randomized study. Of 176 patients who received nimodipine, 2 mg/h iv for 2 day, 53% had a favorable outcome (moderate or good recovery). Of 175 control patients, 49% had a favorable outcome. This difference was not statistically significant buf does not exclude the possibility that a study of a larger number of patients could show a clinically useful benefit.

AB - We studied the efficacy of nimodipine in severely head-injured patients in a randomized study. Of 176 patients who received nimodipine, 2 mg/h iv for 2 day, 53% had a favorable outcome (moderate or good recovery). Of 175 control patients, 49% had a favorable outcome. This difference was not statistically significant buf does not exclude the possibility that a study of a larger number of patients could show a clinically useful benefit.

KW - SUBARACHNOID HEMORRHAGE

KW - PRETREATMENT

M3 - Article

VL - 9

SP - S545-S550

JO - Journal of Neurotrauma

JF - Journal of Neurotrauma

SN - 0897-7151

T2 - 9TH ANNUAL MEETING OF THE NEUROTRAUMA SOC

Y2 - 9 November 1991 through 10 November 1991

ER -

A RANDOMIZED TRIAL OF NIMODIPINE IN SEVERE HEAD-INJURY - HIT-I

Abstract

Keywords

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