A relaxin-based nanotherapeutic strategy for liver fibrosis

Jonathan A Fallowfield; Prakash Ramachandran

doi:10.1038/s41565-020-00832-w

A relaxin-based nanotherapeutic strategy for liver fibrosis

Jonathan A Fallowfield, Prakash Ramachandran

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Targeting of the peptide hormone relaxin to injured mouse liver, via a nanoparticle/gene therapy approach, switches pro-fibrotic hepatic macrophages to a restorative phenotype that orchestrate tissue repair.

Original language	English
Journal	Nature Nanotechnology
Early online date	25 Jan 2021
DOIs	https://doi.org/10.1038/s41565-020-00832-w
Publication status	E-pub ahead of print - 25 Jan 2021

Access to Document

10.1038/s41565-020-00832-w

Fallowfield_NV_on_Huang_revised_2Accepted author manuscript, 52.5 KB

https://pubmed.ncbi.nlm.nih.gov/33495619/

Cite this

@article{060fbc4cbf7542b0b345f3819c70bc0f,

title = "A relaxin-based nanotherapeutic strategy for liver fibrosis",

abstract = "Targeting of the peptide hormone relaxin to injured mouse liver, via a nanoparticle/gene therapy approach, switches pro-fibrotic hepatic macrophages to a restorative phenotype that orchestrate tissue repair.",

author = "Fallowfield, {Jonathan A} and Prakash Ramachandran",

year = "2021",

month = jan,

day = "25",

doi = "10.1038/s41565-020-00832-w",

language = "English",

journal = "Nature Nanotechnology",

issn = "1748-3387",

publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - A relaxin-based nanotherapeutic strategy for liver fibrosis

AU - Fallowfield, Jonathan A

AU - Ramachandran, Prakash

PY - 2021/1/25

Y1 - 2021/1/25

N2 - Targeting of the peptide hormone relaxin to injured mouse liver, via a nanoparticle/gene therapy approach, switches pro-fibrotic hepatic macrophages to a restorative phenotype that orchestrate tissue repair.

AB - Targeting of the peptide hormone relaxin to injured mouse liver, via a nanoparticle/gene therapy approach, switches pro-fibrotic hepatic macrophages to a restorative phenotype that orchestrate tissue repair.

U2 - 10.1038/s41565-020-00832-w

DO - 10.1038/s41565-020-00832-w

M3 - Article

SN - 1748-3387

JO - Nature Nanotechnology

JF - Nature Nanotechnology

ER -

A relaxin-based nanotherapeutic strategy for liver fibrosis

Abstract / Description of output

Access to Document

Fingerprint

Cite this