A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

Esther S Oh; Oluwaseun Akeju; Michael Avidan; Colm Cunningham; Kathleen M Hayden; Richard Jones; Ara Khachaturian; Babar Kahn; Edward R Marcantonio; Dale M Needham; Karin J. Neufeld; Louise Rose; Jessica Spence; Zoe Tieges; Phillip  Vlisides; Sharon K. Inouye

doi:10.1002/alz.12076

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

Esther S Oh, Oluwaseun Akeju, Michael Avidan, Colm Cunningham, Kathleen M Hayden, Richard Jones, Ara Khachaturian, Babar Kahn, Edward R Marcantonio, Dale M Needham, Karin J. Neufeld, Louise Rose, Jessica Spence, Zoe Tieges, Phillip Vlisides, Sharon K. Inouye

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Abstract / Description of output

Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is particularly common among older adults, and is closely linked with underlying neurocognitive disorders. Evidence is mounting that intervening on delirium may represent an important opportunity for delaying the onset or progression of dementia. To accelerate the current understanding of delirium, the Network for Investigation of Delirium: Unifying Scientists (NIDUS) held a conference "Advancing Delirium Research: A Scientific Think Tank" in June 2019. This White Paper encompasses the major knowledge and research gaps identified at the conference: advancing delirium definition and measurement, understanding delirium pathophysiology, and prevention and treatment of delirium. A roadmap of research priorities is proposed to advance the field in a systematic, interdisciplinary, and coordinated fashion. A call is made for an international consortium and biobank targeted to delirium, as well as a public health campaign to advance the field.

Original language	English
Journal	Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Volume	16
Issue number	5
DOIs	https://doi.org/10.1002/alz.12076 https://doi.org/10.1002/alz.12076
Publication status	Published - 14 Apr 2020

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Oh, E. S., Akeju, O., Avidan, M., Cunningham, C., Hayden, K. M., Jones, R., Khachaturian, A., Kahn, B., Marcantonio, E. R., Needham, D. M., Neufeld, K. J., Rose, L., Spence, J., Tieges, Z., Vlisides, P., & Inouye, S. K. (2020). A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 16(5). https://doi.org/10.1002/alz.12076, https://doi.org/10.1002/alz.12076

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title = "A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank",

abstract = "Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is particularly common among older adults, and is closely linked with underlying neurocognitive disorders. Evidence is mounting that intervening on delirium may represent an important opportunity for delaying the onset or progression of dementia. To accelerate the current understanding of delirium, the Network for Investigation of Delirium: Unifying Scientists (NIDUS) held a conference {"}Advancing Delirium Research: A Scientific Think Tank{"} in June 2019. This White Paper encompasses the major knowledge and research gaps identified at the conference: advancing delirium definition and measurement, understanding delirium pathophysiology, and prevention and treatment of delirium. A roadmap of research priorities is proposed to advance the field in a systematic, interdisciplinary, and coordinated fashion. A call is made for an international consortium and biobank targeted to delirium, as well as a public health campaign to advance the field.",

author = "Oh, {Esther S} and Oluwaseun Akeju and Michael Avidan and Colm Cunningham and Hayden, {Kathleen M} and Richard Jones and Ara Khachaturian and Babar Kahn and Marcantonio, {Edward R} and Needham, {Dale M} and Neufeld, {Karin J.} and Louise Rose and Jessica Spence and Zoe Tieges and Phillip Vlisides and Inouye, {Sharon K.}",

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Oh, ES, Akeju, O, Avidan, M, Cunningham, C, Hayden, KM, Jones, R, Khachaturian, A, Kahn, B, Marcantonio, ER, Needham, DM, Neufeld, KJ, Rose, L, Spence, J, Tieges, Z, Vlisides, P & Inouye, SK 2020, 'A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank', Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 16, no. 5. https://doi.org/10.1002/alz.12076, https://doi.org/10.1002/alz.12076

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T1 - A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

AU - Oh, Esther S

AU - Akeju, Oluwaseun

AU - Avidan, Michael

AU - Cunningham, Colm

AU - Hayden, Kathleen M

AU - Jones, Richard

AU - Khachaturian, Ara

AU - Kahn, Babar

AU - Marcantonio, Edward R

AU - Needham, Dale M

AU - Neufeld, Karin J.

AU - Rose, Louise

AU - Spence, Jessica

AU - Tieges, Zoe

AU - Vlisides, Phillip

AU - Inouye, Sharon K.

PY - 2020/4/14

Y1 - 2020/4/14

N2 - Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is particularly common among older adults, and is closely linked with underlying neurocognitive disorders. Evidence is mounting that intervening on delirium may represent an important opportunity for delaying the onset or progression of dementia. To accelerate the current understanding of delirium, the Network for Investigation of Delirium: Unifying Scientists (NIDUS) held a conference "Advancing Delirium Research: A Scientific Think Tank" in June 2019. This White Paper encompasses the major knowledge and research gaps identified at the conference: advancing delirium definition and measurement, understanding delirium pathophysiology, and prevention and treatment of delirium. A roadmap of research priorities is proposed to advance the field in a systematic, interdisciplinary, and coordinated fashion. A call is made for an international consortium and biobank targeted to delirium, as well as a public health campaign to advance the field.

AB - Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is particularly common among older adults, and is closely linked with underlying neurocognitive disorders. Evidence is mounting that intervening on delirium may represent an important opportunity for delaying the onset or progression of dementia. To accelerate the current understanding of delirium, the Network for Investigation of Delirium: Unifying Scientists (NIDUS) held a conference "Advancing Delirium Research: A Scientific Think Tank" in June 2019. This White Paper encompasses the major knowledge and research gaps identified at the conference: advancing delirium definition and measurement, understanding delirium pathophysiology, and prevention and treatment of delirium. A roadmap of research priorities is proposed to advance the field in a systematic, interdisciplinary, and coordinated fashion. A call is made for an international consortium and biobank targeted to delirium, as well as a public health campaign to advance the field.

U2 - 10.1002/alz.12076

DO - 10.1002/alz.12076

M3 - Article

SN - 1552-5260

VL - 16

JO - Alzheimer's & Dementia: The Journal of the Alzheimer's Association

JF - Alzheimer's & Dementia: The Journal of the Alzheimer's Association

IS - 5

ER -

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

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