Abstract / Description of output
The biosynthesis of the meroterpenoid guajadial was previously hypothesized to occur via a hetero-Diels-Alder reaction between caryophyllene and an o-quinone methide. This hypothesis has been verified via the biomimetic synthesis of guajadial and psidial A in an aqueous three-component coupling reaction, between caryophyllene, benzaldehyde, and diformylphloroglucinol.
Original language | English |
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Pages (from-to) | 1676-1679 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 12 |
Issue number | 8 |
DOIs | |
Publication status | Published - 16 Apr 2010 |