A simple method for the alpha-oxygenation of aldehydes

C S  Beshara; A  Hall; R L  Jenkins; T C  Jones; R T  Parry; S P  Thomas; N C O  Tomkinson

doi:10.1039/b418101h

A simple method for the alpha-oxygenation of aldehydes

C S Beshara, A Hall, R L Jenkins, T C Jones, R T Parry, S P Thomas, N C O Tomkinson

Research output: Contribution to journal › Article › peer-review

Abstract

A mild, efficient and general method for the chemospecific alpha-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding alpha-oxygenated carbonyl via a proposed pericyclic rearrangement process.

Original language	English
Pages (from-to)	1478-1480
Number of pages	3
Journal	Chemical Communications
Issue number	11
DOIs	https://doi.org/10.1039/b418101h
Publication status	Published - 2005

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10.1039/b418101h

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title = "A simple method for the alpha-oxygenation of aldehydes",

abstract = "A mild, efficient and general method for the chemospecific alpha-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding alpha-oxygenated carbonyl via a proposed pericyclic rearrangement process.",

author = "Beshara, {C S} and A Hall and Jenkins, {R L} and Jones, {T C} and Parry, {R T} and Thomas, {S P} and Tomkinson, {N C O}",

year = "2005",

doi = "10.1039/b418101h",

language = "English",

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journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - A simple method for the alpha-oxygenation of aldehydes

AU - Beshara, C S

AU - Hall, A

AU - Jenkins, R L

AU - Jones, T C

AU - Parry, R T

AU - Thomas, S P

AU - Tomkinson, N C O

PY - 2005

Y1 - 2005

N2 - A mild, efficient and general method for the chemospecific alpha-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding alpha-oxygenated carbonyl via a proposed pericyclic rearrangement process.

AB - A mild, efficient and general method for the chemospecific alpha-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding alpha-oxygenated carbonyl via a proposed pericyclic rearrangement process.

U2 - 10.1039/b418101h

DO - 10.1039/b418101h

M3 - Article

SN - 1359-7345

SP - 1478

EP - 1480

JO - Chemical Communications

JF - Chemical Communications

IS - 11

ER -

A simple method for the alpha-oxygenation of aldehydes

Abstract

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