A simple method for the alpha-oxygenation of aldehydes

C S Beshara, A Hall, R L Jenkins, T C Jones, R T Parry, S P Thomas, N C O Tomkinson

Research output: Contribution to journalArticlepeer-review

Abstract

A mild, efficient and general method for the chemospecific alpha-oxygenation of aldehydes is described. Treatment of a series of aldehydes with N-tert-butyl-O-benzoyl hydroxylamine hydrochloride gives the corresponding alpha-oxygenated carbonyl via a proposed pericyclic rearrangement process.

Original languageEnglish
Pages (from-to)1478-1480
Number of pages3
JournalChemical Communications
Issue number11
DOIs
Publication statusPublished - 2005

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