A study of SPECT/CT camera stability for quantitative imaging

Wendy A McDougald, Robert S Miyaoka, Adam M Alessio, Robert L Harrison, Thomas K Lewellen

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

BACKGROUND: The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for quantitative SPECT. Using a cylindrical water phantom filled with measured amounts of (99m)Tc, factors were calculated to convert counts/cc to activity/cps. Measurements were made over an 18-month period. System sensitivity data calculated from (57)Co daily quality assurance (DQA) flood acquisitions were then compared to the (99m)Tc calibration factors to determine the relationship of the factors.

RESULTS: The coefficient of variation is 2.7 % for the (99m)Tc cylinder conversion factors and 2.6 % for the (57)Co DQA flood data. The greatest difference between the cylinder conversion factors and the flood data is less than 3 %.

CONCLUSIONS: Based on the results, the camera was stable within 3 % over an 18-month time period. The daily flood source acquisitions can be a reliable source for tracking camera stability and may provide information on updating the calibration factor for quantitative imaging.

Original languageEnglish
Pages (from-to)14
JournalEJNMMI physics
Issue number1
Early online date29 Jul 2016
Publication statusPublished - Dec 2016


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