A sub-group of patients with hospital-acquired pneumonia do not require broad-spectrum gram-negative antimicrobial coverage

Clark D Russell, Ed Whittaker, Dominic P Dee, Eilidh Farquhar, Alba Saenz de Villaverde, Morgan H Evans, Ian F Laurenson, Claire L Mackintosh, Muge Cevik

Research output: Contribution to journalArticlepeer-review

Abstract

Amongst 200 patients developing HAP outwith the ICU, 61% were treated empirically without broad-spectrum gram-negative coverage, with clinical cure in 69.7%. Lower disease severity markers(SIRS, hypoxia, tachypnoea, neutrophilia) and absence of diabetes mellitus and prior doxycycline treatment (but not time to HAP onset) identified patients not requiring broad-spectrum gram-negative coverage.

Original languageEnglish
JournalClinical Infectious Diseases
Early online date8 Apr 2020
DOIs
Publication statusE-pub ahead of print - 8 Apr 2020

Fingerprint

Dive into the research topics of 'A sub-group of patients with hospital-acquired pneumonia do not require broad-spectrum gram-negative antimicrobial coverage'. Together they form a unique fingerprint.

Cite this