A TAD Closer to Understanding Dosage Compensation

Andrew J Wood; Wendy A Bickmore

doi:10.1016/j.devcel.2015.05.021

A TAD Closer to Understanding Dosage Compensation

Research output: Contribution to journal › Article › peer-review

Abstract

Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.

Original language	English
Pages (from-to)	498-9
Number of pages	2
Journal	Developmental Cell
Volume	33
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2015.05.021
Publication status	Published - 8 Jun 2015

Access to Document

10.1016/j.devcel.2015.05.021

3 Finished

Chromosomal instability during normal and condensin II deficient haematopoiesis
Wood, A.
UK-based charities
1/02/14 → 31/01/19
Project: Research
The role of spatial nuclear organisation in genome function
Bickmore, W.
1/04/12 → 31/03/18
Project: Research
CROATIA PROGRAMME
Wright, A., Adams, I., Aligianis, I., Baldock, R., Bickmore, W., Caceres, J., Dorin, J., Dunlop, M., FitzPatrick, D., Haley, C., Hastie, N., Hill, B., Jackson, I., Jackson, A., Kudla, G., Meehan, R., O'Connell, M., Overton, I., Patton, E., Taylor, M., Tenesa, A. & Van Heyningen, V.
MRC
1/04/12 → 31/07/13
Project: Research

Cite this

@article{7d0228f9a452417188272849861b0646,

title = "A TAD Closer to Understanding Dosage Compensation",

abstract = "Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.",

author = "Wood, {Andrew J} and Bickmore, {Wendy A}",

year = "2015",

month = jun,

day = "8",

doi = "10.1016/j.devcel.2015.05.021",

language = "English",

volume = "33",

pages = "498--9",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - A TAD Closer to Understanding Dosage Compensation

AU - Wood, Andrew J

AU - Bickmore, Wendy A

PY - 2015/6/8

Y1 - 2015/6/8

N2 - Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.

AB - Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.

U2 - 10.1016/j.devcel.2015.05.021

DO - 10.1016/j.devcel.2015.05.021

M3 - Article

C2 - 26058053

VL - 33

SP - 498

EP - 499

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 5

ER -

A TAD Closer to Understanding Dosage Compensation

Abstract

Access to Document

Fingerprint

Projects

Chromosomal instability during normal and condensin II deficient haematopoiesis

The role of spatial nuclear organisation in genome function

CROATIA PROGRAMME

Cite this