A TAD Closer to Understanding Dosage Compensation

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.

Original languageEnglish
Pages (from-to)498-9
Number of pages2
JournalDevelopmental Cell
Issue number5
Publication statusPublished - 8 Jun 2015


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