A TAD Closer to Understanding Dosage Compensation

Research output: Contribution to journalArticlepeer-review

Abstract

Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.

Original languageEnglish
Pages (from-to)498-9
Number of pages2
JournalDevelopmental Cell
Volume33
Issue number5
DOIs
Publication statusPublished - 8 Jun 2015

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