Abstract / Description of output
Talin can activate integrins to bind the extracellular matrix and also connect matrix-engaged integrins to the actin cytoskeleton. New work shows that cell spreading can be dissected into three distinct phases according to their differential requirements for talin function.
Original language | English |
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Pages (from-to) | 1017-9 |
Number of pages | 3 |
Journal | Nature Cell Biology |
Volume | 10 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2008 |