A tal(in) of cell spreading

Margaret Frame, Jim Norman

Research output: Contribution to journalArticlepeer-review


Talin can activate integrins to bind the extracellular matrix and also connect matrix-engaged integrins to the actin cytoskeleton. New work shows that cell spreading can be dissected into three distinct phases according to their differential requirements for talin function.
Original languageEnglish
Pages (from-to)1017-9
Number of pages3
JournalNature Cell Biology
Issue number9
Publication statusPublished - 2008

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