A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study

Ian Buysschaert, Kathryn F Carruthers, Donald R Dunbar, Gilian Peuteman, Ernst Rietzschel, Ann Belmans, Ann Hedley, Tim De Meyer, Andrzej Budaj, Frans Van de Werf, Diether Lambrechts, Keith A A Fox

Research output: Contribution to journalArticlepeer-review

Abstract

Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI). Here, we evaluated whether this variant also contributes to recurrent MI or cardiac death following an acute coronary syndrome (ACS).
Original languageEnglish
Pages (from-to)1132-41
Number of pages10
JournalEuropean Heart Journal
Volume31
Issue number9
DOIs
Publication statusPublished - 2010

Keywords

  • Chromosome 9p21
  • Rs1333049
  • Genetics
  • Acute coronary syndrome
  • Myocardial infarction
  • Plaque rupture

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