A virus-neutralising monoclonal antibody expressed in the milk of transgenic mice

A F Kolb; J Webster; C B Whitelaw; S G Siddell

doi:10.1007/978-1-4615-1325-4_61

A virus-neutralising monoclonal antibody expressed in the milk of transgenic mice

A F Kolb, J Webster, C B Whitelaw, S G Siddell

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).

Original language	English
Pages (from-to)	411-4
Number of pages	4
Journal	Advances in Experimental Medicine and Biology
Volume	494
DOIs	https://doi.org/10.1007/978-1-4615-1325-4_61
Publication status	Published - 2001

Keywords

Animals
Antibodies, Monoclonal
Antibodies, Viral
Coronavirus Infections
Female
Mice
Mice, Transgenic
Milk
Murine hepatitis virus
Neutralization Tests
Recombinant Proteins

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10.1007/978-1-4615-1325-4_61

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abstract = "Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).",

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AU - Kolb, A F

AU - Webster, J

AU - Whitelaw, C B

AU - Siddell, S G

PY - 2001

Y1 - 2001

N2 - Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).

AB - Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).

KW - Animals

KW - Antibodies, Monoclonal

KW - Antibodies, Viral

KW - Coronavirus Infections

KW - Female

KW - Mice

KW - Mice, Transgenic

KW - Milk

KW - Murine hepatitis virus

KW - Neutralization Tests

KW - Recombinant Proteins

U2 - 10.1007/978-1-4615-1325-4_61

DO - 10.1007/978-1-4615-1325-4_61

M3 - Article

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VL - 494

SP - 411

EP - 414

JO - Advances in Experimental Medicine & Biology

JF - Advances in Experimental Medicine & Biology

SN - 0065-2598

ER -

A virus-neutralising monoclonal antibody expressed in the milk of transgenic mice

Abstract

Keywords

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