Abattoir-based estimates of mycobacterial infections in Cameroon

Nkongo Franklyn Egbe, Adrian Muwonge, Lucy Ndip, Robert Kelly, Melissa Sander, Vincent N Tanya, Victor Ngu Ngwa, Ian Handel, Amanda Novak, Richard Ngandalo, Stella Mazeri, Kenton L. Morgan, Anne Asuquo, Mark Bronsvoort

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Abstract / Description of output

Mycobacteria cause major diseases including human tuberculosis, bovine tuberculosis and Johne's disease. In livestock, the dominant species is M. bovis causing bovine tuberculosis (bTB), a disease of global zoonotic importance. In this study, we estimated the prevalence of Mycobacteria in slaughter cattle in Cameroon.
A total of 2,346 cattle were examined in a cross-sectional study at four abattoirs in Cameroon. Up to three lesions per animal were collected for further study and a retropharyngeal lymph node was collected from a random sample of non-lesioned animals. Samples were cultured on Lowenstein Jensen media and the BACTEC MGIT 960 system, and identified using the Hain® Genotype kits.
A total of 207/2,346 cattle were identified with bTB-like lesions, representing 4.0% (45/1,129), 11.3% (106/935), 23.8% (38/160) and 14.8% (18/122) of the cattle in the Bamenda, Ngaoundere, Garoua and Maroua abattoirs respectively. The minimum estimated prevalence of M. bovis was 2.8% (1.9-3.9), 7.7% (6.1-9.6), 21.3% (15.2-28.4) and 13.1% (7.7-20.4) in the four abattoirs respectively. One M. tuberculosis and three M. bovis strains were recovered from non-lesioned animals.
The high prevalence of M. bovis is of public health concern and limits the potential control options in this setting without a viable vaccine as an alternative.
Original languageEnglish
Article number24320
JournalScientific Reports
Volume6
Early online date14 Apr 2016
DOIs
Publication statusE-pub ahead of print - 14 Apr 2016

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