TY - JOUR
T1 - Acanthamoeba keratitis due to genotype T11 in a rigid gas permeable contact lens wearer in Spain
AU - Lorenzo-Morales, Jacob
AU - Morcillo-Laiz, Rafael
AU - Martín-Navarro, Carmen Ma
AU - López-Vélez, Rogelio
AU - López-Arencibia, Atteneri
AU - Arnalich-Montiel, Francisco
AU - Maciver, Sutherland K
AU - Valladares, Basilio
AU - Martínez-Carretero, Enrique
N1 - Copyright © 2010 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
PY - 2011
Y1 - 2011
N2 - A case of a 59-year-old Spanish patient who presented with severe ocular pain, blurred vision, eyelid swelling and foreign body sensation in the right eye is reported. She was a regular gas permeable contact lens [corrected] wearer who initially claimed to maintain standard lens care. After exploration, conjunctival injection, dendritiform corneal ulcers and stromal edema were observed. She was initially treated for a possible viral keratitis due to herpes simplex virus using 3% topical acyclovir and 0.1% dexamethasone eye drops 5 times a day. The patient did not respond to this treatment and six weeks later, corneal scrapings were positive for Acanthamoeba genotype T11. She was then treated with chlorhexidine 0.02%, propamidine 0.1% and 1% cycloplegic eye drops hourly which resulted in a significant improvement. After a month, ocular pain decreased and the clinical signs of keratitis ameliorated observed as a diminution of the size of the ulcer and also in the extension and opacity of the corneal infiltrates. The patient has been following this treatment for 3 months and it is possible that she will have to carry on with it for a whole year. To the best of our knowledge, this is the first case of severe keratitis due to Acanthamoeba genotype T11 in Spain .
AB - A case of a 59-year-old Spanish patient who presented with severe ocular pain, blurred vision, eyelid swelling and foreign body sensation in the right eye is reported. She was a regular gas permeable contact lens [corrected] wearer who initially claimed to maintain standard lens care. After exploration, conjunctival injection, dendritiform corneal ulcers and stromal edema were observed. She was initially treated for a possible viral keratitis due to herpes simplex virus using 3% topical acyclovir and 0.1% dexamethasone eye drops 5 times a day. The patient did not respond to this treatment and six weeks later, corneal scrapings were positive for Acanthamoeba genotype T11. She was then treated with chlorhexidine 0.02%, propamidine 0.1% and 1% cycloplegic eye drops hourly which resulted in a significant improvement. After a month, ocular pain decreased and the clinical signs of keratitis ameliorated observed as a diminution of the size of the ulcer and also in the extension and opacity of the corneal infiltrates. The patient has been following this treatment for 3 months and it is possible that she will have to carry on with it for a whole year. To the best of our knowledge, this is the first case of severe keratitis due to Acanthamoeba genotype T11 in Spain .
U2 - 10.1016/j.clae.2010.10.007
DO - 10.1016/j.clae.2010.10.007
M3 - Article
C2 - 21130679
SN - 1476-5411
VL - 34
SP - 83
EP - 86
JO - Contact Lens & Anterior Eye
JF - Contact Lens & Anterior Eye
IS - 2
ER -